BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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10 articles for DP Lane

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Seliciclib (CYC202, R-Roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1.EBI
Cyclacel
Discovery of N-phenyl-4-(thiazol-5-yl)pyrimidin-2-amine aurora kinase inhibitors.EBI
Cyclacel
Interaction of kendomycin and semi-synthetic analogues with the anti-apoptotic protein Bcl-xl.EBI
Merlion Pharmaceuticals
In vitro and in vivo antitumor properties of the cyclin dependent kinase inhibitor CYC202 (R-roscovitine).EBI
Cyclacel, Ltd.
De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits.EBI
Msd
Inhibitors of IRAK4 activityBDB
Merck Sharp & Dohme
Fused bicyclic (hetero)aromatic compounds useful for the treatment of cancersBDB
Redx Pharma
Macrocyclic inhibitors of hepatitis C virusBDB
Janssen Ireland
Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 4: functionalization of the benzopyran A-ring.BDB
Eli Lilly