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62 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of phenoxyindazoles and phenylthioindazoles as ROR¿ inverse agonists.EBI
Galderma R & D
Small molecule inhibitors targeting activator protein 1 (AP-1).EBI
University of Texas Medical Branch
Design, synthesis, and structure-activity analysis of isoform-selective retinoic acid receptor beta ligands.EBI
Acadia Pharmaceuticals
 
Synthesis and biological activities of new heterocyclic aromatic retinoidsEBI
TBA
Toward the development of innovative bifunctional agents to induce differentiation and to promote apoptosis in leukemia: clinical candidates and perspectives.EBI
Aristotle University of Thessaloniki
Synthesis and pharmacological validation of a novel series of non-steroidal FXR agonists.EBI
Phenex Pharmaceuticals
Identification of a chromone-based retinoid containing a polyolefinic side chain via facile synthetic routes.EBI
Temple University
 
Synthesis and structure-activity relationships of potent conformationally restricted retinoid X receptor ligandsEBI
TBA
 
Synthesis and structure-activity relationships of potent retinoid X receptor ligandsEBI
TBA
 
Synthesis and biological activity of 1,2,3,4-tetrahydroquinoline and 3,4-(1H)-dihydroquinolin-2-one analogs of retinoic acidEBI
TBA
 
Synthesis and receptor binding affinity of conformationally restricted retinoic acid analoguesEBI
TBA
 
Synthesis of highly potent RXR-specific retinoids: The use of a cyclopropyl group as a double bond isostereEBI
TBA
 
Synthesis and pharmacological activity of conformationally restricted, acetylenic retinoid analogsEBI
TBA
 
Differential RXR & RAR activity of stilbene retinoid analogs bearing thiazole and imidazole carboxylic acidsEBI
TBA
 
N-linked analogs of retinoid O-glucuronides: potential cancer chemopreventive/chemotherapeutic agentsEBI
TBA
 
Structural basis for the differential RXR & RAR activity of stilbene retinoid analogsEBI
TBA
Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives.EBI
University of Lille
Ligand recognition by RAR and RXR receptors: binding and selectivity.EBI
Universidad De Santiago De Compostela
Design and synthesis of benzofused heterocyclic RXR modulators.EBI
Eli Lilly
Design and synthesis of novel RXR-selective modulators with improved pharmacological profile.EBI
Ligand Pharmaceuticals
Design and synthesis of fluorinated RXR modulators.EBI
Eli Lilly
Novel (2E,4E,6Z)-7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta-2,4,6-trienoic acid retinoid X receptor modulators are active in models of type 2 diabetes.EBI
Ligand Pharmaceuticals
Retinoic acid receptor ligands based on the 6-cyclopropyl-2,4-hexadienoic acid.EBI
Ligand Pharmaceuticals
Synthesis and biological activity of retinoic acid receptor-alpha specific amides.EBI
Allergan
Enantioselective syntheses of potent retinoid X receptor ligands: differential biological activities of individual antipodes.EBI
Allergan
An unhydrolyzable analogue of N-(4-hydroxyphenyl)retinamide. synthesis and preliminary biological studies.EBI
The Ohio State University
Syntheses and evaluation of quinoline derivatives as novel retinoic acid receptor alpha antagonists.EBI
Eisai
Phenylcyclohexene and phenylcyclohexadiene substituted compounds having retinoid antagonist activity.EBI
Allergan
Syntheses and evaluation of naphthalenyl- and chromenyl-pyrrolyl-benzoic acids as potent and selective retinoic acid receptor alpha agonists.EBI
Eisai
Novel retinoic acid receptor alpha agonists: syntheses and evaluation of pyrazole derivatives.EBI
Eisai
Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation.EBI
Goethe University Frankfurt
Syntheses and structure-activity relationships of 5,6,7, 8-tetrahydro-5,5,8,8-tetramethyl-2-quinoxaline derivatives with retinoic acid receptor alpha agonistic activity.EBI
Eisai
Structure-activity relationship studies of novel heteroretinoids: induction of apoptosis in the HL-60 cell line by a novel isoxazole-containing heteroretinoid.EBI
Università
Heteroarotinoids inhibit head and neck cancer cell lines in vitro and in vivo through both RAR and RXR retinoic acid receptors.EBI
University of Oklahoma Health Sciences Center
A new class of potent RAR antagonists: dihydroanthracenyl, benzochromenyl and benzothiochromenyl retinoids.EBI
Allergan
Stereoselective synthesis and receptor activity of conformationally defined retinoid X receptor selective ligands.EBI
Allergan
High affinity retinoic acid receptor antagonists: analogs of AGN 193109.EBI
Allergan
Synthesis of retinoid X receptor-specific ligands that are potent inducers of adipogenesis in 3T3-L1 cells.EBI
Ligand Pharmaceuticals
Synthesis and characterization of heteroarotinoids demonstrate structure specificity relationships.EBI
University of Oklahoma Health Sciences Center
Regulation of retinoidal actions by diazepinylbenzoic acids. Retinoid synergists which activate the RXR-RAR heterodimers.EBI
University of Tokyo
Identification of retinoic acid receptor beta subtype specific agonists.EBI
Allergan
Synthesis and structure-activity relationships of retinoid X receptor selective diaryl sulfide analogs of retinoic acid.EBI
Allergan
Identification of the first retinoid X, receptor homodimer antagonist.EBI
Ligand Pharmaceuticals
Identification of a retinoic acid receptor alpha subtype specific agonist.EBI
Allergan
Discovery of novel retinoic acid receptor agonists having potent antiproliferative activity in cervical cancer cells.EBI
Ligand Pharmaceuticals
Retinoic acid receptor beta,gamma-selective ligands: synthesis and biological activity of 6-substituted 2-naphthoic acid retinoids.EBI
Pharmaceutical Research Institute
Synthesis, structure-affinity relationships, and biological activities of ligands binding to retinoic acid receptor subtypes.EBI
Cird Galderma
Conformational effects on retinoid receptor selectivity. 1. Effect of 9-double bond geometry on retinoid X receptor activity.EBI
Sri International
Synthesis of high specific activity [3H]-9-cis-retinoic acid and its application for identifying retinoids with unusual binding properties.EBI
Ligand Pharmaceuticals
Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids.EBI
Ligand Pharmaceuticals
Synthesis and structure-activity relationships of stilbene retinoid analogs substituted with heteroaromatic carboxylic acids.EBI
Allergan
Synthesis and characterization of a highly potent and effective antagonist of retinoic acid receptors.EBI
Allergan
Identification of highly potent retinoic acid receptor alpha-selective antagonists.EBI
Allergan
Sulfoximines as potent ROR? inverse agonists.EBI
Nestle Skin Health
Probing biological activity through structural modelling of ligand-receptor interactions of 2,4-disubstituted thiazole retinoids.EBI
Helwan University
Structure-based design of Trifarotene (CD5789), a potent and selective RAR? agonist for the treatment of acne.EBI
Nestle Skin Health
Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry.EBI
St. John'S University
Bicycloheteroaryl-heteroaryl-benzoic acid compounds as retinoic acid receptor beta (RARβ) agonistsBDB
King''S College London
Cyclohexylamine derivatives having β2 adrenergic agonist and M3 muscarinic antagonist activitiesBDB
Almirall
Alkoxy compounds for disease treatmentBDB
Acucela
Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists.BDB
Institute of Genetics and Molecular and Cellular Biology (Igbmc)
Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.BDB
Cnrs