18 articles for KM Shokat
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIß.
University of California
Discovery and structure of a new inhibitor scaffold of the autophagy initiating kinase ULK1.
University of California
Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii.
Washington University
A surface on the androgen receptor that allosterically regulates coactivator binding.
University of California
Structure-guided development of affinity probes for tyrosine kinases using chemical genetics.
University of California
The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors.
Medical Research Council-Laboratory of Molecular Biology
Protein kinase C epsilon regulates gamma-aminobutyrate type A receptor sensitivity to ethanol and benzodiazepines through phosphorylation of gamma2 subunits.
University of California San Francisco
Structural bioinformatics-based design of selective, irreversible kinase inhibitors.
University of California
Drugging the Next Undruggable KRAS Allele-Gly12Asp.
University of California San Francisco
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
Qbi Covid-19 Research Group (Qcrg)
Inhibition of Calcium Dependent Protein Kinase 1 (CDPK1) by Pyrazolopyrimidine Analogs Decreases Establishment and Reoccurrence of Central Nervous System Disease by Toxoplasma gondii.
University of California
N-formylpyrazolines and N-benzoylpyrazolines as novel inhibitors of mammalian cathepsin B and cathepsin H.
Kurukshetra University
Discovery of pyrrolopyridine-pyridone based inhibitors of Met kinase: synthesis, X-ray crystallographic analysis, and biological activities.
Bristol-Myers Squibb
The structure of dimeric ROCK I reveals the mechanism for ligand selectivity.
Vertex Pharmaceuticals