35 articles for H Zheng
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Cmpds
Data
Article Title
Organization
59
Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases.
Intra-Cellular Therapies
27
9-Dihydroerythromycins as non-antibiotic motilin receptor agonists.
Kosan Biosciences
25
Structure-activity relationships of 9-substituted-9-dihydroerythromycin-based motilin agonists: optimizing for potency and safety.
Kosan Biosciences
7
Nicotinic acid receptor agonists differentially activate downstream effectors.
Arena Pharmaceuticals
5
Synthesis and biological evaluation of novel 5-benzylidenethiazolidine-2,4-dione derivatives for the treatment of inflammatory diseases.
Sichuan University
32
Molecular docking and QSAR study on steroidal compounds as aromatase inhibitors.
Tianjin University of Science and Technology
9
Novel indoline-1- or 3,4-dihydroquinoline-1(2H)-substituted carbothiohydrazides as TPO receptor agonists.
Shanghai Hengrui Pharmaceuticals
5
Synthesis and biological evaluation of oxoindolin-3-ylidene ethyl benzothiohydrazides as non-peptide TPO mimics.
Shanghai Hengrui Pharmaceuticals
1
Site-activated multifunctional chelator with acetylcholinesterase and neuroprotective-neurorestorative moieties for Alzheimer's therapy.
Institute of Science
5
Halogenated retinoid derivatives as dual RARα and RXRα modulators for treating acute promyelocytic leukemia cells.
Xiamen University
2
Discovery of Novel PROTAC-Based HPK1 Degraders with High Potency and Selectivity for Cancer Immunotherapy.
Huadong Medicine
2
Design and Evaluation of 3-Phenyloxetane Derivative Agonists of the Glucagon-Like Peptide-1 Receptor.
Huadong Medicine Company Limited
2
The Development of a Highly Potent and Selective Human Toll-like Receptor 2 Agonist: Synthesis and Biological Evaluation of CaLGL-1 and Its Derivatives.
Lanzhou University
39
Discovery of Novel Macrocyclic MERTK/AXL Dual Inhibitors.
University of North Carolina
19
Discovery of ITI-333, a Novel Orally Bioavailable Molecule Targeting Multiple Receptors for the Treatment of Pain and Other Disorders.
Intra-Cellular Therapies, Inc.
30
Alkyl-substituted N-methylaryl-N'-aryl-4-aminobenzamides: A new series of small molecule inhibitors for Wip1 phosphatase.
Niddk
1
A TNF-α blocking peptide that reduces NF-κB and MAPK activity for attenuating inflammation.
Changchun University of Science and Technology
10
Quinazoline-based hydroxamic acid derivatives as dual histone methylation and deacetylation inhibitors for potential anticancer agents.
Tsinghua University
36
UNC5293, a potent, orally available and highly MERTK-selective inhibitor.
University of North Carolina at Chapel Hill
95
Discovery and Optimization of 2
National Center For Advancing Translational Sciences
50
Discovery of furyl/thienyl β-carboline derivatives as potent and selective PDE5 inhibitors with excellent vasorelaxant effect.
Shandong University
6
Terpenoids with vasorelaxant effects from the Chinese liverwort Scapania carinthiaca.
Shandong University
21
Design and synthesis of furyl/thineyl pyrroloquinolones based on natural alkaloid perlolyrine, lead to the discovery of potent and selective PDE5 inhibitors.
Shandong University
6
Synthesis and biological evaluation of 6-hydroxyl C-aryl glucoside derivatives as novel sodium glucose co-transporter 2 (SGLT2) inhibitors.
Shandong University
26
Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition.
Effector Therapeutics
45
Discovery of Potent Orally Active Protease-Activated Receptor 1 (PAR1) Antagonists Based on Andrographolide.
Shandong University
21
Kinase inhibitors and their use in cancer therapy
Technische UniversitÄT Dortmund
40
Benzimidazole derivates useful as inhibitors of mammalian histone deacetylase activity
Kancera
5
1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
University of Michigan