BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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17 articles for RE West

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis and SAR studies of benzimidazolone derivatives as histamine H3-receptor antagonists.EBI
Merck Research Laboratories
Discovery of a potent thiadiazole class of histamine h3 receptor antagonist for the treatment of diabetes.EBI
TBA
Fused bicycles as arylketone bioisosteres leading to potent, orally active thiadiazole H3 antagonists.EBI
Merck Research Laboratories
Synthesis and structure-activity relationship (SAR) study of 4-azabenzoxazole analogues as H3 antagonists.EBI
Merck Research Laboratories
Discovery of a series of potent arylthiadiazole H(3) antagonists.EBI
Merck Research Laboratories
The synthesis and structure-activity relationship of 4-benzimidazolyl-piperidinylcarbonyl-piperidine analogs as histamine H3 antagonists.EBI
Merck Research Laboratories
Reduction of hERG inhibitory activity in the 4-piperidinyl urea series of H3 antagonists.EBI
Merck Research Laboratories
Structural determinants for histamine H(1) affinity, hERG affinity and QTc prolongation in a series of terfenadine analogs.EBI
The Schering Plough Research Institute
Synthesis and structure-activity relationships of 2-(1,4'-bipiperidin-1'-yl)thiazolopyridine as H3 receptor antagonists.EBI
Schering-Plough Research Institute
Benzimidazole-substituted (3-phenoxypropyl)amines as histamine H3 receptor ligands.EBI
The Schering Plough Research Institute
Reduction of CYP450 inhibition in the 4-[(1H-imidazol-4-yl)methyl]piperidine series of histamine H3 receptor antagonists.EBI
The Schering Plough Research Institute
Novel histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine scaffold.EBI
The Schering Plough Research Institute
Dual antagonists of platelet activating factor and histamine. 3. Synthesis, biological activity and conformational implications of substituted N-acyl-bis-arylcycloheptapiperazines.EBI
Schering-Plough Research Institute
Novel H3 receptor antagonists. Sulfonamide homologs of histamine.EBI
Schering-Plough Research Institute
Dual antagonists of platelet activating factor and histamine. Identification of structural requirements for dual activity of N-Acyl-4-(5,6-dihydro-11H-benzo [5,6]cyclohepta-[1,2-b]pyridin-11-ylidene)piperidines.EBI
Schering-Plough
Heterocyclic inhibitors of PTPN11BDB
The University of Texas System
Rigid duplex alpha-cyclodextrin reversibly connected with disulfide bonds. Synthesis and inclusion complexes.BDB
Institute of Organic Chemistry and Biochemistry As Cr