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BindingDB contains 2.6M data for 1.1M Compounds and 8.9K Targets. Of those, 1,179K data for 544K Compounds and 4.4K Targets were curated by BindingDB curators.

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65 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Acetazolamide-like carbonic anhydrase inhibitors with topical ocular hypotensive activity.EBI
Istituto Chimico Internazionale Dr. G. Rende
N-Substituted sulfonamide carbonic anhydrase inhibitors with topical effects on intraocular pressure.EBI
TBA
An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C.EBI
Griffith University
Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters.EBI
Universit£ degli Studi di Firenze
Phosphate Chemical Probes Designed for Location Specific Inhibition of Intracellular Carbonic Anhydrases.EBI
Griffith University
Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I-XIV.EBI
TBA
Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX.EBI
Vilnius University
Substituted thieno[2,3-b]thiophenes and related congeners: Synthesis,-glucuronidase inhibition activity, crystal structure, and POM analyses.EBI
King Saud University
Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes.EBI
Griffith University
Synthesis of C-cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases.EBI
Universidad Nacional de La Plata
Tricyclic sulfonamides incorporating benzothiopyrano[4,3-c]pyrazole and pyridothiopyrano[4,3-c]pyrazole effectively inhibita- andß-carbonic anhydrase: X-ray crystallography and solution investigations on 15 isoforms.EBI
Universit£ di Pisa
Synthesis and carbonic anhydrase inhibitory properties of novel bromophenols and their derivatives including natural products: vidalol B.EBI
Atat£rk University
Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins.EBI
Universit£ degli Studi di Cagliari
Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I-XV.EBI
Universit£ degli Studi di Firenze
Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors.EBI
University of Florida
Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV.EBI
Istituto di Biostrutture e Bioimmagini-CNR
Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids.EBI
Universit£ degli Studi di Firenze
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins.EBI
Universita degli Studi di Firenze
The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors.EBI
Universit£ degli Studi di Firenze
A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases.EBI
Universit£ degli Studi di Firenze
Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors.EBI
Istituto di Biostrutture e Bioimmagini-CNR
Carbonic anhydrases as targets for medicinal chemistry.EBI
Universit£ degli Studi di Firenze
Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I.EBI
Universit£ degli Studi di Firenze
Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors.EBI
Kochi Medical School
New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II.EBI
Universit£ degli Studi di Firenze
Structure-activity relationships for the interaction of 5,10-dihydroindeno[1,2-b]indole derivatives with human and bovine carbonic anhydrase isoforms I, II, III, IV and VI.EBI
Ondokuz Mayis University
Synthesis and carbonic anhydrase inhibitory properties of novel cyclohexanonyl bromophenol derivatives.EBI
Artvin£oruh University
Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against humana- and bacterial/fungalß-carbonic anhydrases.EBI
Ecole Nationale Sup£rieure de Chimie de Montpellier
Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.EBI
Universit£ degli Studi di Firenze
In vitro inhibition ofa-carbonic anhydrase isozymes by some phenolic compounds.EBI
Gumushane University
Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata.EBI
Centre Scientifique de Monaco
Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule.EBI
Universita degli Studi di Firenze
The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.EBI
University of Tampere and Tampere University Hospital
Glycomimetic Based Approach toward Selective Carbonic Anhydrase Inhibitors.EBI
Universit£ di Firenze
Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects.EBI
University of Florence
Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms.EBI
Vilnius University
Pyrrolidinone-bearing methylated and halogenated benzenesulfonamides as inhibitors of carbonic anhydrases.EBI
Kaunas University of Technology
Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies.EBI
Universit£ degli Studi di Firenze
Inhibition of human carbonic anhydrase isoforms I-XIV with sulfonamides incorporating fluorine and 1,3,5-triazine moieties.EBI
Universit£ degli Studi di Firenze
Benzenesulfonamides with pyrimidine moiety as inhibitors of human carbonic anhydrases I, II, VI, VII, XII, and XIII.EBI
Vilnius University
Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.EBI
University of Florida
Famotidine, an Antiulcer Agent, Strongly Inhibits EBI
University of Florence
Benzimidazole design, synthesis, and docking to build selective carbonic anhydrase VA inhibitors.EBI
Vilnius University
Design of two-tail compounds with rotationally fixed benzenesulfonamide ring as inhibitors of carbonic anhydrases.EBI
Vilnius University
Bortezomib inhibits mammalian carbonic anhydrases.EBI
Universit£ degli Studi di Firenze
Pharmacological actions of a novel, high-affinity, and selective human dopamine D(3) receptor antagonist, SB-277011-A.BDB
SmithKline Beecham Pharmaceuticals Ltd
SR 142801, the first potent non-peptide antagonist of the tachykinin NK3 receptor.BDB
Sanofi Recherche
Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.BDB
Duke University
7-[3-(4-[2,3-Dimethylphenyl]piperazinyl)propoxy]-2(1H)-quinolinone (OPC-4392), a presynaptic dopamine autoreceptor agonist and postsynaptic D2 receptor antagonist.BDB
Tokushima Research Institute
Detection of a novel serotonin receptor subtype (5-HT1E) in human brain: interaction with a GTP-binding protein.BDB
Albany Medical College
Characterization of the striatal M2 muscarinic receptor mediating inhibition of cyclic AMP using selective antagonists: a comparison with the brainstem M2 receptor.BDB
Abbott Laboratories
Pharmacological characterization of the M1 muscarinic receptors expressed in murine fibroblast B82 cells.BDB
University of Arizona