18 articles for E Zhang
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Structure-based design, SAR analysis and antitumor activity of PI3K/mTOR dual inhibitors from 4-methylpyridopyrimidinone series.
Pfizer
Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Ka and mTOR.
Pfizer
Discovery of a series of 2-(1H-pyrazol-1-yl)pyridines as ALK5 inhibitors with potential utility in the prevention of dermal scarring.
Pfizer
The discovery of fluoropyridine-based inhibitors of the factor VIIa/TF complex--Part 2.
Pfizer
Recent advances in the exploration of oxazolidinone scaffolds from compound development to antibacterial agents and other bioactivities.
Zhengzhou University
Equipotent activity in both enantiomers of a series of ketopiperazine-based renin inhibitors.
Pfizer
Discovery of RO7185876, a Highly Potent γ-Secretase Modulator (GSM) as a Potential Treatment for Alzheimer's Disease.
F. Hoffmann-La Roche
Bound structures of novel P3-P1' beta-strand mimetic inhibitors of thrombin.
Michigan State University
Potent and selective thrombin inhibitors incorporating the constrained arginine mimic l-3-piperidyl(N-guanidino)alanine at P1.
Corvas International
NOTA analogue: A first dithiocarbamate inhibitor of metallo-β-lactamases.
Zhengzhou University
