74 articles for JH Kim
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
Organization
Soluble epoxide hydrolase inhibitors of indolinone alkaloids and phenolic derivatives from Cimicifuga dahurica (Turcz.) Maxim.
Chungnam National University
Identification of the First Selective Activin Receptor-Like Kinase 1 Inhibitor, a Reversible Version of L-783277.
Korea University
3,4-Dihydroquinazoline derivatives inhibit the activities of cholinesterase enzymes.
Kyung Hee University
Improvement of therapeutic index of phosphodiesterase type IV inhibitors as anti-Asthmatics.
Lead Gene
Syntheses and evaluation of pyrido[2,3-dlpyrimidine-2,4-diones as PDE 4 inhibitors.
Korea Institute of Science and Technology
Synthesis and T-type calcium channel-blocking effects of aryl(1,5-disubstituted-pyrazol-3-yl)methyl sulfonamides for neuropathic pain treatment.
Korea Institute of Science & Technology (Kist)
Pyrazolodiazepine derivatives with agonist activity toward Drosophila RYamide receptor.
Gwangju Institute of Science and Technology
Constituents of the seeds of Cassia tora with inhibitory activity on soluble expoxide hydrolease.
Chungnam National University
Highly potent and selective pyrazolylpyrimidines as Syk kinase inhibitors.
Kangwon National University
Soluble epoxide hydrolase inhibitory activity of anthraquinone components from Aloe.
Chungnam National University
Use of molecular modeling aided design to dial out hERG liability in adenosine A(2A) receptor antagonists.
Merck Research Laboratories
Discovery of Orally Available Runt-Related Transcription Factor 3 (RUNX3) Modulators for Anticancer Chemotherapy by Epigenetic Activation and Protein Stabilization.
Yonsei University
Neuraminidase inhibitory activities of quaternary isoquinoline alkaloids from Corydalis turtschaninovii rhizome.
Chungnam National University
The dipeptide H-Trp-Glu-OH (WE) shows agonistic activity to peroxisome proliferator-activated protein-a and reduces hepatic lipid accumulation in lipid-loaded H4IIE cells.
Korea University
Identification of 2-aminooxazole amides as acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) inhibitors through scaffold hopping strategy.
Merck Research Laboratories
Reversal of P-glycoprotein-mediated MDR by 5,7,3',4',5'-pentamethoxyflavone and SAR.
Chosun University
C-7 analogues of progesterone as potent inhibitors of the P-glycoprotein efflux pump.
Georgetown University School of Medicine
Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis.
Seoul National University
Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases.
Korea Research Institute of Bioscience and Biotechnology
Structure-activity relationships and optimization of 3,5-dichloropyridine derivatives as novel P2X(7) receptor antagonists.
Gwangju Institute of Science and Technology (Gist)
Chemical constituents from the aerial parts of Aster koraiensis with protein glycation and aldose reductase inhibitory activities.
Korean Institute of Oriental Medicine (Kiom)
Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities.
Korea Research Institute of Bioscience and Biotechnology
Characteristic of neuraminidase inhibitory xanthones from Cudrania tricuspidata.
Graduate School of Gyeongsang National University
Putative therapeutic agents for the learning and memory deficits of people with Down syndrome.
Research Center Idrtech
Sulfonamide chalcone as a new class of alpha-glucosidase inhibitors.
Gyeongsang National University
Design, synthesis and binding affinity of 3'-fluoro analogues of Cl-IB-MECA as adenosine A3 receptor ligands.
Seoul National University
A prenylated flavonol, sophoflavescenol: a potent and selective inhibitor of cGMP phosphodiesterase 5.
Korea Institute of Science & Technology
Synthesis and antihypertensive activity of pyrimidin-4(3H)-one derivatives as losartan analogue for new angiotensin II receptor type 1 (AT1) antagonists.
Kyung Hee University
Probes for narcotic receptor mediated phenomena. Part 42: synthesis and in vitro pharmacological characterization of the N-methyl and N-phenethyl analogues of the racemic ortho-c and para-c oxide-bridged phenylmorphans.
National Institute On Drug Abuse and The National Institute On Alcohol Abuse and Alcoholism
Synthesis and evaluation of benzoxazole derivatives as 5-lipoxygenase inhibitors.
Ewha Womans University
Probing cell-division phenotype space and Polo-like kinase function using small molecules.
Rockefeller University
Synthesis and biological evaluation of 3-aminopyrrolidine derivatives as CC chemokine receptor 2 antagonists.
Yangji Chemicals
QSAR analysis of pyrazolidine-3,5-diones derivatives as Dyrk1A inhibitors.
Inje University
Synthesis and structure-activity relationships of novel, substituted 5,6-dihydrodibenzo[a,g]quinolizinium P2X7 antagonists.
Institute of Science and Technology (Gist)
Discovery of a novel BLT2 antagonist for the treatment of inflammatory airway diseases.
Korea University
DW71177: A novel [1,2,4]triazolo[4,3-a]quinoxaline-based potent and BD1-Selective BET inhibitor for the treatment of acute myeloid leukemia.
Korea Research Institute of Chemical Technology
Synthesis of (aryloxyacetylamino)-isonicotinic/nicotinic acid analogues as potent hypoxia-inducible factor (HIF)-1alpha inhibitors.
Molecular Cancer Research Center
Design, synthesis, and biological evaluation of HDAC6 inhibitors targeting L1 loop and serine 531 residue.
Keimyung University
Design, Synthesis, and Biological Evaluation of New 2,6,7-Substituted Purine Derivatives as Toll-like Receptor 7 Agonists for Intranasal Vaccine Adjuvants.
Gwangju Institute of Science and Technology
Discovery of 3-Phenyl Indazole-Based Novel Chemokine-like Receptor 1 Antagonists for the Treatment of Psoriasis.
Gwangju Institute of Science and Technology (GIST)
Development and Therapeutic Potential of NUAKs Inhibitors.
University of Science and Technology (Ust)
Rational design of an indolebutanoic acid derivative as a novel aldose reductase inhibitor based on docking and 3D QSAR studies of phenethylamine derivatives.
Yonsei University
Synthesis of 6-formyl-pyridine-2-carboxylate derivatives and their telomerase inhibitory activities.
Seoul National University
Identification, characterization, kinetics, and molecular docking of flavonoid constituents from Archidendron clypearia (Jack.) Nielsen leaves and twigs.
Chungnam National University
Discovery of Leucyladenylate Sulfamates as Novel Leucyl-tRNA Synthetase (LRS)-Targeted Mammalian Target of Rapamycin Complex 1 (mTORC1) Inhibitors.
Seoul National University
A novel class of highly potent, selective, and non-peptidic inhibitor of Ras farnesyltransferase (FTase).
Lgci
3-Aryl-4-aryloyl-1-(1H-imidazol-5-yl)methylpyrrole, a novel class of farnesyltransferase inhibitors.
Lgci
Synthesis and evaluation of 6-pyrazoylamido-3N-substituted azabicyclo[3,1,0]hexane derivatives as T-type calcium channel inhibitors for treatment of neuropathic pain.
Korea Institute of Science & Technology (Kist)
Identification of a Unique Resorcylic Acid Lactone Derivative That Targets Both Lymphangiogenesis and Angiogenesis.
Korea University
Synthesis and Characterization of an A6-A11 Methylene Thioacetal Human Insulin Analogue with Enhanced Stability.
University of Utah
Structure-Based Discovery of Novel Cyclophilin A Inhibitors for the Treatment of Hepatitis C Virus Infections.
Chonnam National University
Dieckol, a SARS-CoV 3CL(pro) inhibitor, isolated from the edible brown algae Ecklonia cava.
Korea Research Institute of Bioscience and Biotechnology
Development of anti-coxsackievirus agents targeting 3C protease.
Gwangju Institute of School of Life Sciences
Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition.
Korea Research Institute of Bioscience and Biotechnology
Development of selective inhibitors for the treatment of rheumatoid arthritis: (R)-3-(3-(Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)-3-oxopropanenitrile as a JAK1-selective inhibitor.
Seoul National University
Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy.
Seoul National University
Inhibition Potential of Cycloartane-Type Glycosides from the Roots of Cimicifuga dahurica against Soluble Epoxide Hydrolase.
Chungnam National University
Discovery of simplified leucyladenylate sulfamates as novel leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors.
Seoul National University
Synthesis and biological evaluation of fluoro-substituted 3,4-dihydroquinazoline derivatives for cytotoxic and analgesic effects.
Kyung Hee University
Substituted pyrazolo[1,5-a]pyridine compound, composition containing the same and use thereof
Shenzhen Targetrx
Heteroaryl-substituted sulfonamide compounds and their use as therapeutic agents
Xenon Pharmaceuticals
Methods and compositions of 4-substituted benzoylpiperazine-1-substituted carbonyls as β-catenin/B-cell lymphoma 9 inhibitors
University of Utah
[1,6]naphthyridine compounds and derivatives as CDK8/CDK19 inhibitors
Boehringer Ingelheim International
4,5,6-trisubstituted indazole derivatives, and preparation method and pharmaceutical use thereof
TBA
Substituted isoindolin-1-ones and 2,3-dihydro-1h-pyrrolo[3,4-c]pyridin-1-ones as HPK1 antagonists
Nimbus Saturn