BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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17 articles for RG Smith

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
 
The design and synthesis of orally active short duration spiroindane growth hormone secretagoguesEBI
TBA
Modeling directed design and biological evaluation of quinazolinones as non-peptidic growth hormone secretagogues.EBI
Merck Research Laboratories
Heterocyclic derivatives of 2-(3,5-dimethylphenyl)tryptamine as GnRH receptor antagonists.EBI
Merck Research Laboratories
2-(3,5-Dimethylphenyl)tryptamine derivatives that bind to the GnRH receptor.EBI
Merck Research Laboratories
A potent, nonpeptidyl 1H-quinolone antagonist for the gonadotropin-releasing hormone receptor.EBI
Merck Research Laboratories
SAR studies of novel 5-substituted 2-arylindoles as nonpeptidyl GnRH receptor antagonists.EBI
Merck Research Laboratories
Initial structure-activity relationship of a novel class of nonpeptidyl GnRH receptor antagonists: 2-arylindoles.EBI
Merck Research Laboratories
Quinolones as gonadotropin releasing hormone (GnRH) antagonists: simultaneous optimization of the C(3)-aryl and C(6)-substituents.EBI
Merck Research Laboratories
Potent antagonists of gonadotropin releasing hormone receptors derived from quinolone-6-carboxamides.EBI
Merck Research Laboratories
Investigation of the 4-O-alkylamine substituent of non-peptide quinolone GnRH receptor antagonists.EBI
Merck Research Laboratories
Identification and initial structure-activity relationships of a novel non-peptide quinolone GnRH receptor antagonist.EBI
Merck Research Laboratories
Potent 3-spiropiperidine growth hormone secretagogues.EBI
Merck Research Laboratories
Peptidomimetic growth hormone secretagogues. Design considerations and therapeutic potential.EBI
Merck Research Laboratories
Development of a high specific activity sulfur-35-labeled sulfonamide radioligand that allowed the identification of a new growth hormone secretagogue receptor.EBI
Merck Research Laboratories
Synthesis and anxiolytic activity of a series of pyrazino[1,2-a][1,4]benzodiazepine derivatives.EBI
TBA
Terphenyl-Based Bak BH3 alpha-helical proteomimetics as low-molecular-weight antagonists of Bcl-xL.BDB
Yale University
Synthesis and in vitro evaluation of sulfonamide isatin Michael acceptors as small molecule inhibitors of caspase-6.BDB
Washington University