BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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23 articles for N Sawyer

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Comparison between two classes of selective EP(3) antagonists and their biological activities.EBI
Merck Frosst Centre For Therapeutic Research
Structure-activity relationship studies on ortho-substituted cinnamic acids, a new class of selective EP(3) antagonists.EBI
Merck Frosst Centre For Therapeutic Research
New indole amide derivatives as potent CRTH2 receptor antagonists.EBI
Merck Frosst
Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases.EBI
Merck Frosst Centre For Therapeutic Research
Azaindoles as potent CRTH2 receptor antagonists.EBI
Merck Frosst Centre For Therapeutic Research
Design, synthesis, and evaluation of novel 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonists.EBI
Wuxi Pharmatech
 
Structure activity relationships of tetrahydrocannabinol analogues on human cannabinoid receptorsEBI
TBA
 
New class of potent ligands for the human peripheral cannabinoid receptorEBI
TBA
 
Discovery of MK-0476, a potent and orally active leukotriene D4 receptor antagonist devoid of peroxisomal enxyme inductionEBI
TBA
 
Discovery of L-740,515, a potent thienopyridine cysLT1 receptor (LTD4 receptor) antagonistEBI
TBA
 
Evolution of a series of non-quinoline leukotriene D4 receptor antagonist; synthesis and sar of benzothiazoles and thiazoles substituted benzyl alcohols as potent LTD4 antagonistsEBI
TBA
 
The discovery of L-699,392, a novel potent and orally active leukotriene D4 receptor antagonistEBI
TBA
Discovery of potent and selective DP1 receptor antagonists in the azaindole series.EBI
Merck Frosst Centre For Therapeutic Research
Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524).EBI
Merck Frosst Canada
Identification of an indole series of prostaglandin D2 receptor antagonists.EBI
Merck Frosst Canada
2,3-Diarylthiophenes as selective EP1 receptor antagonists.EBI
Merck Frosst Centre For Therapeutic Research
Structure-activity relationship of triaryl propionic acid analogues on the human EP3 prostanoid receptor.EBI
Merck Frosst Centre For Therapeutic Research
Structure-activity relationship of biaryl acylsulfonamide analogues on the human EP(3) prostanoid receptor.EBI
Merck Frosst Centre For Therapeutic Research
Structure-activity relationship on the human EP3 prostanoid receptor by use of solid-support chemistry.EBI
Merck Frosst Canada
New class of biphenylene dibenzazocinones as potent ligands for the human EP1 prostanoid receptor.EBI
Merck Frosst Centre For Therapeutic Research
A series of non-quinoline cysLT1 receptor antagonists: SAR study on pyridyl analogs of Singulair.EBI
Merck Frosst Center For Therapeutic Research
Flaviviral protease inhibitors identified by fragment-based library docking into a structure generated by molecular dynamics.BDB
University of Zurich
Discovery and initial SAR of arylsulfonylpiperazine inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1).BDB
Amgen