BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 772K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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17 articles for DJ Cohen

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
9
Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 9: Synthesis, characterization and molecular modeling of pyridinyl isosteres of N-BPE-8-CAC (1), a high affinity ligand for opioid receptors.EBI
Rensselaer Polytechnic Institute
24
Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 8. High affinity ligands for opioid receptors in the picomolar Ki range: oxygenated N-(2-[1,1'-biphenyl]-4-ylethyl) analogues of 8-CAC.EBI
Rensselaer Polytechnic Institute
42
Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors.EBI
Harvard Medical School
22
Syntheses of novel high affinity ligands for opioid receptors.EBI
Rensselaer Polytechnic Institute
41
Syntheses and opioid receptor binding properties of carboxamido-substituted opioids.EBI
Rensselaer Polytechnic Institute
20
Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 6: Opioid receptor binding properties of cyclic variants of 8-carboxamidocyclazocine.EBI
Rensselaer Polytechnic Institute
21
Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 5. Opioid receptor binding properties of N-((4'-phenyl)-phenethyl) analogues of 8-CAC.EBI
Institute
17
Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 4. Opioid receptor binding properties of 8-[N-(4'-phenyl)-phenethyl)carboxamido] analogues of cyclazocine and ethylketocycalzocine.EBI
Rensselaer Polytechnic Institute
9
Selective protection and functionalization of morphine: synthesis and opioid receptor binding properties of 3-amino-3-desoxymorphine derivatives.EBI
Rensselaer Polytechnic Institute
10
Synthesis and opioid receptor affinity of morphinan and benzomorphan derivatives: mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine dependence.EBI
Harvard Medical School
29
Mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan.EBI
Harvard Medical School
8
3-Carboxamido analogues of morphine and naltrexone. synthesis and opioid receptor binding properties.EBI
Pharmacia
16
8-Aminocyclazocine analogues: synthesis and structure-activity relationships.EBI
Institute
11
Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 7: syntheses and opioid receptor properties of cyclic variants of cyclazocine.EBI
Rensselaer Polytechnic Institute
43
Syntheses and opioid receptor binding affinities of 8-amino-2,6-methano-3-benzazocines.EBI
Rensselaer Polytechnic Institute
14
8-Carboxamidocyclazocine analogues: redefining the structure-activity relationships of 2,6-methano-3-benzazocines.EBI
Rensselaer Polytechnic Institute
15
Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: exploration of 6-6 fused rings as alternative S1 moieties.BDB
Daiichi Sankyo