BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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13 articles for SC Goodacre

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Identification of an Orally Bioavailable, Potent, and Selective Inhibitor of GlyT1.EBI
TBA
Imidazo[1,2-a]pyrimidines as functionally selective and orally bioavailable GABA(A)alpha2/alpha3 binding site agonists for the treatment of anxiety disorders.EBI
Merck Sharp Laboratory
Optimisation of a series of potent, selective and orally bioavailable GlyT1 inhibitors.EBI
Merck Sharp and Dohme Research Laboratories
Imidazo[1,2-a]pyrimidines as functionally selective GABA(A) ligands.EBI
Merck Sharp and Dohme Research Laboratories
Imidazo[1,2-a]pyrazin-8-ones, imidazo[1,2-d][1,2,4]triazin-8-ones and imidazo[2,1-f][1,2,4]triazin-8-ones as alpha2/alpha3 subtype selective GABA A agonists for the treatment of anxiety.EBI
Merck Sharp and Dohme Research Laboratories
Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling.EBI
Genentech
Fluorination of 3-(3-(piperidin-1-yl)propyl)indoles and 3-(3-(piperazin-1-yl)propyl)indoles gives selective human 5-HT1D receptor ligands with improved pharmacokinetic profiles.EBI
Merck Sharp & Dohme Research Laboratories
TRICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOFBDB
Shanghaitech University
Benzenesulfonylbenazamide compound for inhibiting BCL-2 protein and composition and use thereofBDB
Shenzhen Targetrx
Urease inhibitors from Hypericum oblongifolium WALL.BDB
University of Peshawar
In silico binding analysis and SAR elucidations of newly designed benzopyrazine analogs as potent inhibitors of thymidine phosphorylase.BDB
Universiti Teknologi Mara (Uitm)
Pyrazolopyrimidine JAK inhibitor compounds and methodsBDB
Genentech