26 articles for A Purohit
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Synthesis and evaluation of analogues of estrone-3-O-sulfamate as potent steroid sulfatase inhibitors.
University of Bath
Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template.
University of Bath
Novel inhibitors of 17beta-hydroxysteroid dehydrogenase type 1: templates for design.
University of Bath
Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents.
University of Bath
Modification of estrone at the 6, 16, and 17 positions: novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.
University of Bath
E-ring modified steroids as novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.
University of Bath
Novel and potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitors.
University of Bath
Synthesis and biological activity of the superestrogen (E)-17-oximino-3-O-sulfamoyl-1,3,5(10)-estratriene: x-ray crystal structure of (E)-17-oximino-3-hydroxy-1,3,5(10)-estratriene.
University of Bath
Active site directed inhibition of estrone sulfatase by nonsteroidal coumarin sulfamates.
University of Bath
Estrone sulfamates: potent inhibitors of estrone sulfatase with therapeutic potential.
University of Bath
2-Alkylsulfanyl estrogen derivatives: synthesis of a novel class of multi-targeted anti-tumour agents.
University of Bath
Docking studies of sulphamate inhibitors of estrone sulphatase in human carbonic anhydrase II.
University of Bath
Phosphonates and thiophosphonates as sulfate surrogates: synthesis of estrone 3-methylthiophosphonate, a potent inhibitor of estrone sulfatase
TBA
Hybrid Dual Aromatase-Steroid Sulfatase Inhibitors with Exquisite Picomolar Inhibitory Activity
TBA
3,17-disubstituted 2-alkylestra-1,3,5(10)-trien-3-ol derivatives: synthesis, in vitro and in vivo anticancer activity.
University of Bath
2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity.
University of Bath
A-ring-substituted estrogen-3-O-sulfamates: potent multitargeted anticancer agents.
University of Bath
A novel 18 beta-glycyrrhetinic acid analogue as a potent and selective inhibitor of 11 beta-hydroxysteroid dehydrogenase 2.
University of Bath
Binding of tetrahydrocarboline derivatives at human 5-HT5A receptors.
Virginia Commonwealth University
Pyrrolidine-2, 5-dione derivatives, pharmaceutical compositions and methods for use as IDO1 inhibitors
Iteos Therapeutics
5-membered nitrogen containing heterocyclic derivatives and pharmaceutical compositions comprising the same
Kissei Pharmaceutical
Discovery of SCH446211 (SCH6): a new ketoamide inhibitor of the HCV NS3 serine protease and HCV subgenomic RNA replication.
Schering-Plough Research Institute
Novel 4-anilinoquinazolines with C-7 basic side chains: design and structure activity relationship of a series of potent, orally active, VEGF receptor tyrosine kinase inhibitors.
Astrazeneca