66 articles for HJ Kim
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism.
Hanyang University
3,4-Dihydroquinazoline derivatives inhibit the activities of cholinesterase enzymes.
Kyung Hee University
5-HT7 receptor modulators: Amino groups attached to biphenyl scaffold determine functional activity.
Yonsei University
Synthesis, structure determination, and biological evaluation of phenylsulfonyl hydrazide derivatives as potential anti-inflammatory agents.
Kyung Hee University
Discovery ofa-mangostin as a novel competitive inhibitor against mutant isocitrate dehydrogenase-1.
Dongguk University
Discovery of Orally Available Runt-Related Transcription Factor 3 (RUNX3) Modulators for Anticancer Chemotherapy by Epigenetic Activation and Protein Stabilization.
Yonsei University
In vitro induction of apoptosis by isosclerone from marine-derived fungus Aspergillus fumigatus.
Pukyong National University
Lead optimization of a novel series of imidazo[1,2-a]pyridine amides leading to a clinical candidate (Q203) as a multi- and extensively-drug-resistant anti-tuberculosis agent.
Institut Pasteur Korea
Synthesis and structure-activity relationships of carboxylic acid derivatives of pyridoxal as P2X receptor antagonists.
Gwangju Institute of Science and Technology
Cyclic tetrapeptides with thioacetate tails or intramolecular disulfide bridge as potent inhibitors of histone deacetylases.
Graduate School of Life Science and Systems Engineering
Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies.
TBA
Dipeptidyl peptidase-4 inhibitor withß-amino amide scaffold: synthesis, SAR and biological evaluation.
Dong-A Pharm.
Preclinical metabolism of LB42908, a novel farnesyl transferase inhibitor, and its effects on the cytochrome P450 isozyme activities.
Lg Life Sciences R & D Center
Cholinestrase inhibitory effects of geranylated flavonoids from Paulownia tomentosa fruits.
Graduate School of Gyeongsang National University
Novel GSK-3beta inhibitors from sequential virtual screening.
Korea Institute of Science and Technology
A prenylated flavonol, sophoflavescenol: a potent and selective inhibitor of cGMP phosphodiesterase 5.
Korea Institute of Science & Technology
Synthesis and HIV-1 integrase inhibitory activities of caffeoylglucosides.
Institute of Science and Technology
Novel substrate-based inhibitors of human glutamate carboxypeptidase II with enhanced lipophilicity.
Academy of Sciences of The Czech Republic
Design and synthesis of novel arylpiperazine derivatives containing the imidazole core targeting 5-HT(2A) receptor and 5-HT transporter.
Green Cross
Discovery of DA-1229: a potent, long acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes.
Dong-A Pharm.
Synthesis of cinnamoyl ketoamides as hybrid structures of antioxidants and calpain inhibitors.
College of Pharmacy Kyung Hee University
Arylpiperazine-containing pyrimidine 4-carboxamide derivatives targeting serotonin 5-HT(2A), 5-HT(2C), and the serotonin transporter as a potential antidepressant.
Green Cross
Further optimization of novel pyrrole 3-carboxamides for targeting serotonin 5-HT(2A), 5-HT(2C), and the serotonin transporter as a potential antidepressant.
Green Cross
Arylpiperazine-containing pyrrole 3-carboxamide derivatives targeting serotonin 5-HT(2A), 5-HT(2C), and the serotonin transporter as a potential antidepressant.
Green Cross
Bicyclic peptides as potent inhibitors of histone deacetylases: optimization of alkyl loop length.
Graduate School of Life Science and Systems Engineering
Synthesis of tyrosinase inhibitory (4-oxo-4H-pyran-2-yl)acrylic acid ester derivatives.
Institute of Science and Technology
Synthesis and antibacterial activities of baulamycin A inspired derivatives.
Korea University
Synthesis and biological evaluation of O4'-benzyl-hispidol derivatives and analogs as dual monoamine oxidase-B inhibitors and anti-neuroinflammatory agents.
Mansoura University
Design and synthesis of 4-quinolinone 2-carboxamides as calpain inhibitors.
Kyung Hee University
In vitro and in vivo anti-pigmentation effects of 2-mercaptobenzimidazoles as nanomolar tyrosinase inhibitors on mammalian cells and zebrafish embryos: Preparation of pigment-free zebrafish embryos.
Pusan National University
Discovery of PPARγ and glucocorticoid receptor dual agonists to promote the adiponectin and leptin biosynthesis in human bone marrow mesenchymal stem cells.
Seoul National University
Optimization and evaluation of pyridinyl vinyl sulfones as Nrf2 activator for the antioxidant and anti-inflammatory effects.
Korea Institute of Science and Technology (KIST)
Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis.
Korea Institute of Science & Technology (Kist)
Discovery of GCC5694A: A potent and selective sodium glucose co-transporter 2 inhibitor for the treatment of type 2 diabetes.
Gc Pharma
Identification of a Target Site for Covalent Inhibition of Protein Phosphohistidine Phosphatase 1.
Ulsan National Institute of Science and Technology (UNIST)
Discovery of G Protein-Biased Ligands against 5-HT
Korea Institute of Science and Technology
Optimization and Evaluation of Novel Antifungal Agents for the Treatment of Fungal Infection.
Korea Institute of Science & Technology (Kist)
Discovery of G Protein-Biased Antagonists against 5-HT
Korea Institute of Science and Technology
Discovery of a Novel Highly Selective Histamine H4 Receptor Antagonist for the Treatment of Atopic Dermatitis.
Sungkyunkwan University
In vitro synergistic anticancer activity of the combination of T-type calcium channel blocker and chemotherapeutic agent in A549 cells.
Kyung Hee University
Development and optimization of halogenated vinyl sulfones as Nrf2 activators for the treatment of Parkinson's disease.
Korea Institute of Science & Technology (Kist)
Discovery and Structure-Activity Relationships of Novel Template, Truncated 1'-Homologated Adenosine Derivatives as Pure Dual PPARγ/δ Modulators.
Seoul National University
Insights of a Lead Optimization Study and Biological Evaluation of Novel 4-Hydroxytamoxifen Analogs as Estrogen-Related Receptor γ (ERRγ) Inverse Agonists.
Daegu-Gyeongbuk Medical Innovation Foundation
Kojyl cinnamate esters are peroxisome proliferator-activated receptor α/γ dual agonists.
Seoul National University
Evaluation of anti-depressant effects of phthalazinone-based triple-acting small molecules against 5-HT
Korea Institute of Science and Technology
Optimization of Vinyl Sulfone Derivatives as Potent Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Activators for Parkinson's Disease Therapy.
Korea Institute of Science & Technology (Kist)
A novel chalcone derivative as Nrf2 activator attenuates learning and memory impairment in a scopolamine-induced mouse model.
Korea Institute of Science & Technology (Kist)
Antioxidant, Anti-inflammatory, and Neuroprotective Effects of Novel Vinyl Sulfonate Compounds as Nrf2 Activator.
Korea Institute of Science & Technology (Kist)
A new flavonol glycoside gallate ester from Acer okamotoanum and its inhibitory activity against human immunodeficiency virus-1 (HIV-1) integrase.
Korea Institute of Science & Technology
Vanillic acid glycoside and quinic acid derivatives from Gardeniae Fructus.
Korea Institute of Science and Technology
Identification of crizotinib derivatives as potent SHIP2 inhibitors for the treatment of Alzheimer's disease.
Korea Institute of Science and Technology
Identification of quinone analogues as potential inhibitors of picornavirus 3C protease in vitro.
Korea Research Institute of Chemical Technology
Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy.
Yonsei University
Synthesis and biological evaluation of fluoro-substituted 3,4-dihydroquinazoline derivatives for cytotoxic and analgesic effects.
Kyung Hee University
Substituted 3-arylsulfonyl-pyrazolo[1,5-A]pyrimidines, serotonin 5-HT6 receptor antagonists and methods for the production and use thereof
TBA
Inactivation of a novel neuropeptide Y/peptide YY receptor gene in primate species.
Yamanouchi Pharmaceutical
Selective activation of inhibitory G-protein alpha-subunits by partial agonists of the human 5-HT1A receptor.
Medical University of South Carolina