PMID
Data
Article Title
Organization
3,4-Dihydroquinazoline derivatives inhibit the activities of cholinesterase enzymes.

Kyung Hee University
Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease.

Korea Institute of Science and Technology
Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening.

Korea Research Institute of Chemical Technology
Synthesis of a series of unsaturated ketone derivatives as selective and reversible monoamine oxidase inhibitors.

Korea Institute of Science and Technology
Discovery of novel 2,5-dioxoimidazolidine-based P2X(7) receptor antagonists as constrained analogues of KN62.

Gwangju Institute of Science and Technology (Gist)
Studies examining the relationship between the chemical structure of protoxin II and its activity on voltage gated sodium channels.

Purdue Pharma
Potential neuroprotective flavonoid-based inhibitors of CDK5/p25 from Rhus parviflora.

Kyung Hee University
Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis.

Seoul National University
Silicon switch approach in TRPV1 antagonist MK-056 and its analogues.

Sookmyung Women'S University
Biarylpyrazolyl oxadiazole as potent, selective, orally bioavailable cannabinoid-1 receptor antagonists for the treatment of obesity.

Green Cross
Discovery of benzimidazole-indazole derivatives as potent FLT3-tyrosine kinase domain mutant kinase inhibitors for acute myeloid leukemia.

Gwangju Institute of Science and Technology (GIST)
Optimization and evaluation of pyridinyl vinyl sulfones as Nrf2 activator for the antioxidant and anti-inflammatory effects.

Korea Institute of Science and Technology (KIST)
Lead discovery and optimization of T-type calcium channel blockers.

Institute of Science and Technology
Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis.

Korea Institute of Science & Technology (Kist)
Novel diarylsulfonylurea derivatives as potent antimitotic agents.

Lg Life Sciences
Optimization and Evaluation of Novel Antifungal Agents for the Treatment of Fungal Infection.

Korea Institute of Science & Technology (Kist)
Secondary Metabolites from the Leather Coral-Derived Fungal Strain

University of Hawai'I At Hilo
Development and optimization of halogenated vinyl sulfones as Nrf2 activators for the treatment of Parkinson's disease.

Korea Institute of Science & Technology (Kist)
Potent Suppressive Effects of 1-Piperidinylimidazole Based Novel P2X7 Receptor Antagonists on Cancer Cell Migration and Invasion.

Gwangju Institute of Science and Technology (Gist)
Adiponectin-Secretion-Promoting Phenylethylchromones from the Agarwood of Aquilaria malaccensis.

Seoul National University
Optimization of Vinyl Sulfone Derivatives as Potent Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Activators for Parkinson's Disease Therapy.

Korea Institute of Science & Technology (Kist)
A novel chalcone derivative as Nrf2 activator attenuates learning and memory impairment in a scopolamine-induced mouse model.

Korea Institute of Science & Technology (Kist)
Antioxidant, Anti-inflammatory, and Neuroprotective Effects of Novel Vinyl Sulfonate Compounds as Nrf2 Activator.

Korea Institute of Science & Technology (Kist)
Synthesis and biological evaluation of picolinamides and thiazole-2-carboxamides as mGluR5 (metabotropic glutamate receptor 5) antagonists.

Korea Institute of Science & Technology (Kist)
Structure-activity relationship studies of pyrimidine-2,4-dione derivatives as potent P2X7 receptor antagonists.

Gwangju Institute of Science and Technology (Gist)
Phenolic compounds with radical scavenging and cyclooxygenase-2 (COX-2) inhibitory activities from Dioscorea opposita.

Seoul National University
Alkamides from the fruits of Piper longum and Piper nigrum displaying potent cell adhesion inhibition.

Korea Research Institute of Bioscience and Biotechnology
Synthesis and biological evaluation of 3-(4-substituted-phenyl)-N-hydroxy-2-propenamides, a new class of histone deacetylase inhibitors.

In2Gen
Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy.

Yonsei University
Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells.

Gwangju Institute of Science and Technology (Gist)
Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against Aβ-induced neurotoxicity.

Korea Institute of Science & Technology (Kist)
Identification of 4-Phenoxyquinoline Based Inhibitors for L1196M Mutant of Anaplastic Lymphoma Kinase by Structure-Based Design.

Korea Advanced Institute of Science and Technology (Kaist)
Pentafluorosulfanyl-substituted amide derivatives, preparation methods thereof and medical uses thereof

Beijing Innocare Pharma Tech
Vasopressin receptor antagonists and products and methods related thereto

Blackthorn Therapeutics
Fused pyrimidine derivatives

Hoffmann-La Roche
Tetrahydronaphthalene derivative

Ono Pharmaceutical
Three-ring PI3K and/or mTOR inhibitor

Zuanzhu Pharma
Triazolopyridazines as PAR1 inhibitors, production thereof, and use as medicaments

Sanofi
Kinetic and thermodynamic rationale for suberoylanilide hydroxamic acid being a preferential human histone deacetylase 8 inhibitor as compared to the structurally similar ligand, trichostatin a.

North Dakota State University
Indolecarboxylic acid derivative having PGD2 receptor antagonistic activity

Shionogi
Optimization of 3-(1H-indazol-3-ylmethyl)-1,5-benzodiazepines as potent, orally active CCK-A agonists.

Glaxo Wellcome Research and Development
(-)-[3H] desmethoxyverapamil labels multiple calcium channel modulator receptors in brain and skeletal muscle membranes: differentiation by temperature and dihydropyridines.

Johns Hopkins University