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38 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery and SAR of N-(1-((substituted piperidin-4-yl)methyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide derivatives: 5-Hydroxytryptamine receptor 4 agonist as a potent prokinetic agent.EBI
Sungkyunkwan University
 
Quaternised renzapride as a potent and selective 5-HT4 receptor agonistEBI
TBA
Identification of multiple 5-HT4 partial agonist clinical candidates for the treatment of Alzheimer's disease.EBI
Pfizer
Pyrrolizidine esters and amides as 5-HT4 receptor agonists and antagonists.EBI
Pfizer
Azaadamantane benzamide 5-HT4 agonists: gastrointestinal prokinetic SC-54750.EBI
Pfizer
5-HT4 receptor ligands: applications and new prospects.EBI
Paris-Sud University
Benzimidazole derivatives. 2. Synthesis and structure-activity relationships of new azabicyclic benzimidazole-4-carboxylic acid derivatives with affinity for serotoninergic 5-HT(3) receptors.EBI
Universidad Complutense
New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists for 5-HT4 receptors.EBI
Cnrs-Biocis
Novel and highly potent 5-HT3 receptor agonists based on a pyrroloquinoxaline structure.EBI
Universit£
 
Serotoninergic 5-HT3 and 5-HT4 receptor activities of dihydrobenzofuran carboxylic acid derivativesEBI
TBA
 
Novel benzimidazole-4-carboxylic acid derivatives as potent and selective 5-HT3 receptor ligandsEBI
TBA
 
Synthesis and pharmacological activity of a macrocyclic benzamideEBI
TBA
 
New aza(nor)adamantanes are agonists at the newly identified serotonin 5-HT4 receptor and antagonists at the 5-HT3 receptorEBI
TBA
New serotonin 5-HT(1A) receptor agonists with neuroprotective effect against ischemic cell damage.EBI
Universidad Complutense De Madrid
Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT(1A)R agonists with selectivity over alpha1-adrenoceptors.EBI
TBA
 
Serotonin 5-HT4 agonist activity of a series of meso-azanoradamantane benzamidesEBI
TBA
 
Design of a potent 5-HT4 receptor agonist with nanomolar affinityEBI
TBA
Synthesis and structure--activity relationship in a class of indolebutylpiperazines as dual 5-HT(1A) receptor agonists and serotonin reuptake inhibitors.EBI
Merck
Bridgehead-methyl analog of SC-53116 as a 5-HT4 agonist.EBI
Pfizer
Design and synthesis of S-(-)-2-[[4-(napht-1-yl)piperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2-a]pyrazine (CSP-2503) using computational simulation. A 5-HT1A receptor agonist.EBI
Universidad Complutense
Benzimidazole derivatives. 3. 3D-QSAR/CoMFA model and computational simulation for the recognition of 5-HT(4) receptor antagonists.EBI
Universidad Complutense
3-D-QSAR/CoMFA and recognition models of benzimidazole derivatives at the 5-HT(4) receptor.EBI
Universidad Complutense
Arylcarbamate derivatives of 1-piperidineethanol as potent ligands for 5-HT4 receptors.EBI
Cnrs-Biocis
Synthesis and SAR of Imidazo[1,5-a]pyridine derivatives as 5-HT4 receptor partial agonists for the treatment of cognitive disorders associated with Alzheimer's disease.EBI
Suven Life Sciences
Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives.EBI
Solvay Duphar
Synthesis, Structure-Activity Relationships, and Preclinical Evaluation of Heteroaromatic Amides and 1,3,4-Oxadiazole Derivatives as 5-HTEBI
Suven Life Sciences
Design and synthesis of newer potential 4-(N-acetylamino)phenol derived piperazine derivatives as potential cognition enhancers.BDB
Panjab University