BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 737K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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11 articles for R Graceffa

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Sulfonamides as Selective NaEBI
Amgen
Structure- and property-based design of aminooxazoline xanthenes as selective, orally efficacious, and CNS penetrable BACE inhibitors for the treatment of Alzheimer's disease.EBI
Amgen
Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors.EBI
Amgen
A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of ß-Secretase.EBI
TBA
Identification of small molecule inhibitors of proline-rich tyrosine kinase 2 (Pyk2) with osteogenic activity in osteoblast cells.EBI
Amgen
Discovery of triazine-benzimidazoles as selective inhibitors of mTOR.EBI
Amgen
The discovery of benzoxazine sulfonamide inhibitors of NaEBI
Amgen
Proteasome activity enhancing compoundsBDB
Proteostasis Therapeutics
Substituted 3-haloallylamine inhibitors of ASSAO and uses thereofBDB
Boehringer Ingelheim International
Oxidase inhibitors and their useBDB
Oryzon Genomics
Effect of N-methyl substitution of the peptide bonds in luteinizing hormone-releasing hormone agonists.BDB
Abbott Laboratories