19 articles for WP Janzen
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
UNC2025, a potent and orally bioavailable MER/FLT3 dual inhibitor.
University of North Carolina at Chapel Hill
Discovery of a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.
University of North Carolina at Chapel Hill
Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosis.
Eshelman School of Pharmacy�Department of Pharmacology�Lineberger Compreh
Pseudo-cyclization through intramolecular hydrogen bond enables discovery of pyridine substituted pyrimidines as new Mer kinase inhibitors.
University of North Carolina at Chapel Hill
Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP.
University of North Carolina at Chapel Hill
Small-molecule ligands of methyl-lysine binding proteins: optimization of selectivity for L3MBTL3.
University of North Carolina at Chapel Hill
Design and synthesis of diarylamines and diarylethers as cytotoxic antitumor agents.
Beijing Institute of Pharmacology & Toxicology
Orally active adenosine A(1) receptor agonists with antinociceptive effects in mice.
University of North Carolina at Chapel Hill
Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia.
TBA
Identification of non-peptide malignant brain tumor (MBT) repeat antagonists by virtual screening of commercially available compounds.
University of North Carolina at Chapel Hill
New hexahydroxybiphenyl derivatives as inhibitors of protein kinase C.
University of North Carolina
Small-molecule ligands of methyl-lysine binding proteins.
University of North Carolina at Chapel Hill
Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines.
University of North Carolina at Chapel Hill
Anti-AIDS Agents, 11. Betulinic Acid and Platanic Acid as Anti-HIV Principles from Syzigium claviflorum, and the Anti-HIV Activity of Structurally Related Triterpenoids
TBA
Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain.
University of North Carolina Eshelman School of Pharmacy
Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation.
Epizyme, Inc.
Synthesis and protein kinase C inhibitory activities of balanol analogs with replacement of the perhydroazepine moiety.
Eli Lilly
The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface.
University of North Carolina
