PMID

Data

Article Title

Organization

Synthesis of oxytocin antagonists containing conformationally constrained amino acids in position 2.

Albert Szent-Gy£Rgyi Medical University

 

Vasopressin trisulphide: synthesis, NMR study and affinity studies with V₁ and V₂ subtypes receptors

TBA

Synthesis and structure-activity relationships of 5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine derivatives: novel arginine vasopressin antagonists.

Central Pharmaceutical Research Institute

Nanomolar-affinity, non-peptide oxytocin receptor antagonists.

Merck Research Laboratories

Arginine-vasopressin analogues with high antidiuretic/vasopressor selectivity. Synthesis, biological activity, and receptor binding affinity of arginine-vasopressin analogues with substitutions in positions 1, 2, 4, 7, and 8.

TBA

Cyclic hexapeptide oxytocin antagonists. Potency-, selectivity-, and solubility-enhancing modifications.

Merck Sharp & Dohme Research Laboratories

Orally active, nonpeptide oxytocin antagonists.

Merck Research Laboratories