BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Donate Now

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

Advanced Search

23 articles for A Kaiser

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor¿ Modulators.EBI
Goethe-University Frankfurt
Anthranilic acid derivatives as novel ligands for farnesoid X receptor (FXR).EBI
Goethe-University Frankfurt
Aminothiazole-featured pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors with improved potency and efficiency in vivo.EBI
Goethe-University Frankfurt
Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3.EBI
Goethe University Frankfurt
Development of Selective Pyrido[2,3-d]pyrimidin-7(8H)-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors.EBI
Goethe University Frankfurt
Development of a Potent and Selective G2A (GPR132) Agonist.EBI
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
Modification of eukaryotic initiation factor 5A from Plasmodium vivax by a truncated deoxyhypusine synthase from Plasmodium falciparum: An enzyme with dual enzymatic properties.EBI
Institute For Medical Parasitology
Structure-Based Design of Dual Partial Peroxisome Proliferator-Activated Receptor γ Agonists/Soluble Epoxide Hydrolase Inhibitors.EBI
Goethe-University
Second-Generation Dual FXR/sEH Modulators with Optimized Pharmacokinetics.EBI
Goethe University Frankfurt
Propranolol Activates the Orphan Nuclear Receptor TLX to Counteract Proliferation and Migration of Glioblastoma Cells.EBI
Goethe-University Frankfurt
Design, Synthesis, and Structure-Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase.EBI
Goethe-University of Frankfurt
First Structure-Activity Relationship Study of Potent BLT2 Agonists as Potential Wound-Healing Promoters.EBI
Fraunhofer Ime
A New FXR Ligand Chemotype with Agonist/Antagonist Switch.EBI
Goethe-University Frankfurt
Design and Structural Optimization of Dual FXR/PPARδ Activators.EBI
Goethe University Frankfurt
Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation.EBI
Goethe University Frankfurt
Structure optimization of a new class of PPARγ antagonists.EBI
Fraunhofer Institute For Molecular Biology and Applied Ecology Ime
Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype.EBI
Goethe-University Frankfurt
A Novel Biphenyl-based Chemotype of Retinoid X Receptor Ligands Enables Subtype and Heterodimer Preferences.EBI
Goethe-University Frankfurt
Computer-Aided Selective Optimization of Side Activities of Talinolol.EBI
Goethe-University of Frankfurt
Boosting Anti-Inflammatory Potency of Zafirlukast by Designed Polypharmacology.EBI
Goethe University Frankfurt
Structural optimization and in vitro profiling of N-phenylbenzamide-based farnesoid X receptor antagonists.EBI
Goethe-University Frankfurt
Nonacidic Farnesoid X Receptor Modulators.EBI
Goethe-University Frankfurt
A Dual Modulator of Farnesoid X Receptor and Soluble Epoxide Hydrolase To Counter Nonalcoholic Steatohepatitis.EBI
Goethe-University Frankfurt