17 articles for C Jamieson
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Structure-Activity Relationships of Small Molecule Autotaxin Inhibitors with a Discrete Binding Mode.
University of Strathclyde
Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA
University of Strathclyde
Development of Autotaxin Inhibitors: An Overview of the Patent and Primary Literature.
University of Strathclyde
Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening.
Glaxosmithkline
The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits.
Glaxosmithkline
Structure based evolution of a novel series of positive modulators of the AMPA receptor.
Merck Research Laboratories
A novel series of positive modulators of the AMPA receptor: structure-based lead optimization.
Merck Research Laboratories
Positive allosteric modulators of thea-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor.
Merck Research Laboratories
Synthesis and Evaluation of Small Molecule Inhibitors of the Androgen Receptor N-Terminal Domain.
University of Strathclyde
Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I-BET432.
Gsk
Structure-Based Design of a Novel Class of Autotaxin Inhibitors Based on Endogenous Allosteric Modulators.
University of Strathclyde
Design and Development of a Macrocyclic Series Targeting Phosphoinositide 3-Kinase δ.
Gsk Medicines Research Centre
Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease.
Glaxosmithkline R&D
Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators.
The Netherlands Institute