27 articles for O Soukup
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease.
University of Bologna
Tetrahydropyranodiquinolin-8-amines as new, non hepatotoxic, antioxidant, and acetylcholinesterase inhibitors for Alzheimer's disease therapy.
University of Sfax
Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation.
Jagiellonian University Medical College
Cardanol-derived AChE inhibitors: Towards the development of dual binding derivatives for Alzheimer's disease.
University of Bras£Lia
Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity.
University Hospital Hradec Kralove
Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation.
University of Hradec Kralove
Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition.
Charles University in Prague
Carltonine-derived compounds for targeted butyrylcholinesterase inhibition.
Charles University
Highly selective butyrylcholinesterase inhibitors related to Amaryllidaceae alkaloids - Design, synthesis, and biological evaluation.
Charles University
Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties.
University of Bras£Lia
7-Azaindole, 2,7-diazaindole, and 1H-pyrazole as core structures for novel anticancer agents with potential chemosensitizing properties.
University Hospital Hradec Kralove
Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer's Disease.
Alma Mater Studiorum - University of Bologna
Huprine Y - Tryptophan heterodimers with potential implication to Alzheimer's disease treatment.
University Hospital Hradec Kralove
2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer's disease.
University Hospital Hradec Kralove
Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors.
University Hospital Hradec Kralove
Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile.
University of Defense
The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators.
UBFC
Novel Sustainable-by-Design HDAC Inhibitors for the Treatment of Alzheimer's Disease.
University of Bras£Lia
Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease.
University of Hradec Kralove
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase.
Alexandria University
Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents.
Institute For Medical Research and Occupational Health
The concept of hybrid molecules of tacrine and benzyl quinolone carboxylic acid (BQCA) as multifunctional agents for Alzheimer's disease.
University of Defence
Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment.
Charles University In Prague