The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 772K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

25 articles for WK Park


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
23
Synthesis of (3S,4S)-4-aminopyrrolidine-3-ol derivatives and biological evaluation for their BACE1 inhibitory activities.EBI
Korea University of Science and Technology
12
Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM).EBI
Korea University of Science and Technology (Ust)
12
Synthesis and biological evaluation of 4-nitroindole derivatives as 5-HT2A receptor antagonists.EBI
Ewha Womans University
20
Novel N-biphenyl-2-ylmethyl 2-methoxyphenylpiperazinylalkanamides as 5-HT7R antagonists for the treatment of depression.EBI
Yonsei University
7
Biological evaluation of tanshindiols as EZH2 histone methyltransferase inhibitors.EBI
Korea Research Institute of Chemical Technology
4
Novel pyrimidoazepine analogs as serotonin 5-HT(2A) and 5-HT(2C) receptor ligands for the treatment of obesity.EBI
Korea Institute of Science and Technology
86
Novel quinazolinone derivatives as 5-HT7 receptor ligands.EBI
Institute of Science and Technology
16
Synthesis of sialyl Lewis X mimetics using the Ugi four-component reaction.EBI
Scripps Research Institute
25
5-HT2c receptor selectivity and structure-activity relationship of N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide analogs.EBI
Korea Institute of Science and Technology
116
Design and synthesis of novel arylpiperazine derivatives containing the imidazole core targeting 5-HT(2A) receptor and 5-HT transporter.EBI
Green Cross
18
1-(Arylsulfonyl)-2,3-dihydro-1H-quinolin-4-one derivatives as 5-HT(6) serotonin receptor ligands.EBI
Korea Research Institute of Chemical Technology
14
Arylpiperazine-containing pyrimidine 4-carboxamide derivatives targeting serotonin 5-HT(2A), 5-HT(2C), and the serotonin transporter as a potential antidepressant.EBI
Green Cross
26
Synthesis and SAR of (piperazin-1-yl-phenyl)-arylsulfonamides: a novel series of atypical antipsychotic agents.EBI
Korea Research Institute of Chemical Technology
57
Further optimization of novel pyrrole 3-carboxamides for targeting serotonin 5-HT(2A), 5-HT(2C), and the serotonin transporter as a potential antidepressant.EBI
Green Cross
31
Synthesis and biological evaluation of 3-aminopyrrolidine derivatives as CC chemokine receptor 2 antagonists.EBI
Yang Ji Chemical Co.
37
Arylpiperazine-containing pyrrole 3-carboxamide derivatives targeting serotonin 5-HT(2A), 5-HT(2C), and the serotonin transporter as a potential antidepressant.EBI
Green Cross
37
Synthesis and biological evaluation of (phenylpiperazinyl-propyl)arylsulfonamides as selective 5-HT(2A) receptor antagonists.EBI
Ewha Womans University
77
Identification of novel serotonin 2C receptor ligands by sequential virtual screening.EBI
Institute of Science and Technology
22
Synthesis and structure-activity relationship of 1H-indole-3-carboxylic acid pyridine-3-ylamides: a novel series of 5-HT2C receptor antagonists.EBI
Korea Research Institute of Chemical Technology
28
Preparation of piperazine derivatives as 5-HT7 receptor antagonists.EBI
Ewha Womans University
23
Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors.EBI
Pfizer
37
Discovery of 3-aryl-3-methyl-1H-quinoline-2,4-diones as a new class of selective 5-HT6 receptor antagonists.EBI
Korea Research Institute of Chemical Technology
8
Naphthofuroquinone derivatives: inhibition of receptor tyrosine kinases.EBI
Korea Research Institute of Chemical Technology
37
Evaluation of anti-depressant effects of phthalazinone-based triple-acting small molecules against 5-HTEBI
Korea Institute of Science and Technology
9
Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against Aβ-induced neurotoxicity.EBI
Korea Institute of Science & Technology (Kist)