The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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13 articles for DM Ferguson


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis and evaluation of xanomeline analogs--probing the wash-resistant phenomenon at the M1 muscarinic acetylcholine receptor.EBI
University of Minnesota
Quantitative three dimensional structure linear interaction energy model of 5'-O-[N-(salicyl)sulfamoyl]adenosine and the aryl acid adenylating enzyme MbtA.EBI
University of Minnesota
Discovery of Imidazoquinolines with Toll-Like Receptor 7/8 Independent Cytokine Induction.EBI
TBA
Toward a structure-based model of salvinorin A recognition of the kappa-opioid receptor.EBI
University of Minnesota
Covalently induced activation of the delta opioid receptor by a fluorogenic affinity label, 7'-(phthalaldehydecarboxamido)naltrindole (PNTI).EBI
University of Minnesota
Investigation of the selectivity of oxymorphone- and naltrexone-derived ligands via site-directed mutagenesis of opioid receptors: exploring the"address" recognition locus.EBI
University of Minnesota
Transformation of a kappa-opioid receptor antagonist to a kappa-agonist by transfer of a guanidinium group from the 5'- to 6'-position of naltrindole.EBI
University of Minnesota
Isosteric replacement of acidic with neutral residues in extracellular loop-2 of the kappa-opioid receptor does not affect dynorphin A(1-13) affinity and function.EBI
University of Minnesota
Molecular docking reveals a novel binding site model for fentanyl at the mu-opioid receptor.EBI
University of Minnesota
Toll-like receptor 7 and 8 imidazoquinoline-based agonist/antagonist pairs.EBI
University of Minnesota
Potent and selective indolomorphinan antagonists of the kappa-opioid receptor.EBI
University of Minnesota
Structure-activity relationship analysis of imidazoquinolines with Toll-like receptors 7 and 8 selectivity and enhanced cytokine induction.EBI
University of Minnesota
Design and Synthesis of N1-Modified Imidazoquinoline Agonists for Selective Activation of Toll-like Receptors 7 and 8.EBI
University of Minnesota