The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

25 articles for B Fischer


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Identification of Highly Promising Antioxidants/Neuroprotectants Based on Nucleoside 5'-Phosphorothioate Scaffold. Synthesis, Activity, and Mechanisms of Action.EBI
Bar-Ilan University
Synthesis and structure-activity relationship of uracil nucleotide derivatives towards the identification of human P2Y6 receptor antagonists.EBI
Bar-Ilan University
2-Hexylthio-ß,¿-CH2-ATP is an effective and selective NTPDase2 inhibitor.EBI
Bar-Ilan University
Highly potent and selective ectonucleotide pyrophosphatase/phosphodiesterase I inhibitors based on an adenosine 5'-(a or¿)-thio-(a,ß- orß,¿)-methylenetriphosphate scaffold.EBI
Bar-Ilan University
Nonhydrolyzable ATP analogues as selective inhibitors of human NPP1: a combined computational/experimental study.EBI
UniversitÉ
Highly efficient biocompatible neuroprotectants with dual activity as antioxidants and P2Y receptor agonists.EBI
Bar-Ilan University
UDP made a highly promising stable, potent, and selective P2Y6-receptor agonist upon introduction of a boranophosphate moiety.EBI
Bar-Ilan University
Identification of a promising drug candidate for the treatment of type 2 diabetes based on a P2Y(1) receptor agonist.EBI
Bar-Ilan University
Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors.EBI
Bar-Ilan University
5-OMe-UDP is a potent and selective P2Y(6)-receptor agonist.EBI
Bar-Ilan University
Identification of hydrolytically stable and selective P2Y(1) receptor agonists.EBI
Bar-Ilan University
Diadenosine and diuridine poly(borano)phosphate analogues: synthesis, chemical and enzymatic stability, and activity at P2Y1 and P2Y2 receptors.EBI
Bar-Ilan University
Molecular recognition in purinergic receptors. 2. Diastereoselectivity of the h-P2Y1-receptor.EBI
Bar-Ilan University
Adenosine 5'-O-(1-boranotriphosphate) derivatives as novel P2Y(1) receptor agonists.EBI
Bar-Ilan University
Novel inhibitors of nucleoside triphosphate diphosphohydrolases: chemical synthesis and biochemical and pharmacological characterizations.EBI
University of Sherbrooke
Molecular recognition of modified adenine nucleotides by the P2Y(1)-receptor. 1. A synthetic, biochemical, and NMR approach.EBI
Bar-Ilan University
2-thioether 5'-O-(1-thiotriphosphate)adenosine derivatives as new insulin secretagogues acting through P2Y-Receptors.EBI
Bar-Ilan University
Structure-activity relationships of N6-benzyladenosine-5'-uronamides as A3-selective adenosine agonists.EBI
National Institute of Diabetes
Boranophosphate isoster controls P2Y-receptor subtype selectivity and metabolic stability of dinucleoside polyphosphate analogues.EBI
Bar-Ilan University
Diadenosine 5',5''-(boranated)polyphosphonate analogues as selective nucleotide pyrophosphatase/phosphodiesterase inhibitors.EBI
Bar-Ilan University
2-MeS-beta,gamma-CCl2-ATP is a potent agent for reducing intraocular pressure.EBI
Bar-Ilan University
A novel insulin secretagogue based on a dinucleoside polyphosphate scaffold.EBI
Bar-Ilan University
Structure-activity relationship study of NPP1 inhibitors based on uracil-N1-(methoxy)ethyl-β-phosphate scaffold.EBI
Bar-Ilan University
Structure-activity relationships of 8-styrylxanthines as A2-selective adenosine antagonists.EBI
National Institute of Diabetes
Highly Selective and Potent Ectonucleotide Pyrophosphatase-1 (NPP1) Inhibitors Based on Uridine 5'-PEBI
Bar-Ilan University