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36 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

Article Title
Antiestrogens. 3. Estrogen receptor affinities and antiproliferative effects in MCF-7 cells of phenolic analogues of trioxifene, [3,4-dihydro-2-(4- methoxyphenyl)-1-naphthalenyl][4-[2-(1-pyrrolidinyl)ethoxy]- phenyl]methanone.EBI
Eli Lilly
17-Desoxy estrogen analogues.EBI
Sri International
Synthesis and biological evaluation of novel thio-substituted chromanes as high-affinity partial agonists for the estrogen receptor.EBI
Novo Nordisk
Synthesis and pharmacology of a novel pyrrolo[2,1,5-cd] indolizine (NNC 45-0095), a high affinity non-steroidal agonist for the estrogen receptor.EBI
Novo Nordisk
Synthesis and estrogen receptor binding affinities of novel pyrrolo[2,1,5-cd]indolizine derivatives.EBI
Novo Nordisk
Synthesis and biological activity of trans-2,3-dihydroraloxifene.EBI
Eli Lilly
Novel nonsteroidal selective estrogen receptor modulators. Carbon and heteroatom replacement of oxygen in the ethoxypiperidine region of raloxifene.EBI
Eli Lilly
Synthesis and estrogen receptor binding affinity of a porphyrin-estradiol conjugate for targeted photodynamic therapy of cancer.EBI
Boston University School of Medicine
Development of progesterone receptor antagonists from 1,2-dihydrochromeno[3,4-f]quinoline agonist pharmacophore.EBI
Ligand Pharmaceuticals
Synthesis and biological activity of 5-methylidene 1,2-dihydrochromeno[3,4-f]quinoline derivatives as progesterone receptor modulators.EBI
Ligand Pharmaceuticals
Nonsteroidal progesterone receptor antagonists based on 6-thiophenehydroquinolines.EBI
Ligand Pharmaceuticals
Estrogen receptor ligands. Part 3: The SAR of dihydrobenzoxathiin SERMs.EBI
Merck Research Laboratories
A novel estrogen receptor ligand template.EBI
Tetrahydroquinoline-based selective estrogen receptor modulators (SERMs).EBI
Eli Lilly
Nonsteroidal androgen receptor agonists based on 4-(trifluoromethyl)-2H-pyrano[3,2-g]quinolin-2-one.EBI
Ligand Pharmaceuticals
New nonsteroidal androgen receptor modulators based on 4-(trifluoromethyl)-2(1H)-pyrrolidino[3,2-g] quinolinone.EBI
Ligand Pharmaceuticals
Discovery of novel quinoline-based estrogen receptor ligands using peptide interaction profiling.EBI
Glaxosmithkline Research & Development
Benzoxepin-derived estrogen receptor modulators: a novel molecular scaffold for the estrogen receptor.EBI
Trinity College Dublin
Benzothiophene and naphthalene derived constrained SERMs.EBI
Eli Lilly
Synthesis and biological evaluation of stilbene-based pure estrogen antagonists.EBI
Universit£T Regensburg
Design, synthesis, and biological evaluation of doxorubicin-formaldehyde conjugates targeted to breast cancer cells.EBI
University of Colorado
Design, synthesis, and in vitro biological evaluation of small molecule inhibitors of estrogen receptor alpha coactivator binding.EBI
University of Illinois
Antiestrogenically active 1,1,2-tris(4-hydroxyphenyl)alkenes without basic side chain: synthesis and biological activity.EBI
Free University of Berlin
Discovery and preclinical characterization of (+)-3-[4-(1- piperidinoethoxy)phenyl]spiro[indene- 1,1'-indane]-5,5'-diol hydrochloride: a promising nonsteroidal estrogen receptor agonist for hot flush.EBI
Dainippon Pharmaceutical
Flexible estrogen receptor modulators: design, synthesis, and antagonistic effects in human MCF-7 breast cancer cells.EBI
Trinity College
Photochemical synthesis of N-arylbenzophenanthridine selective estrogen receptor modulators (serms).EBI
Eli Lilly
Cytotoxicity and antiestrogenicity of a novel series of basic diphenylethylenes.EBI
Synthesis and biological evaluation of 4-(hydroxyalkyl)estradiols and related compounds.EBI
Ohio State University
Structure-activity relationships of selective estrogen receptor modulators: modifications to the 2-arylbenzothiophene core of raloxifene.EBI
Eli Lilly
Steroidal affinity labels of the estrogen receptor. 3. Estradiol 11 beta-n-alkyl derivatives bearing a terminal electrophilic group: antiestrogenic and cytotoxic properties.EBI
Inserm Unit�
(S)-(+)-4-[7-(2,2-dimethyl-1-oxopropoxy)-4-methyl-2-[4-[2-(1-piperidinyl)-ethoxy]phenyl]-2H-1-benzopyran-3-yl]-phenyl 2,2-dimethylpropanoate (EM-800): a highly potent, specific, and orally active nonsteroidal antiestrogen.EBI
Le Centre Hospitalier Universitaire De Qu£Bec
2-(Hydroxyalkyl)estradiols: synthesis and biological evaluation.EBI
Ohio State University
Novel 5-aminoflavone derivatives as specific antitumor agents in breast cancer.EBI
Kyowa Hakko Kogyo
Lead Optimization of Benzoxepin-Type Selective Estrogen Receptor (ER) Modulators and Downregulators with Subtype-Specific ER? and ER? Activity.EBI
Trinity College
Phenolic metabolites of clomiphene: [(E,Z)-2-[4-(1,2-diphenyl-2-chlorovinyl)phenoxy]ethyl]diethylamine. Preparation, electrophilicity, and effects in MCF 7 breast cancer cells.EBI
University of Georgia