BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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12 articles for KR Brunden

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Evaluation of the cyclopentane-1,2-dione as a potential bio-isostere of the carboxylic acid functional group.EBI
University of Pennsylvania
Potent, long-acting cyclopentane-1,3-Dione thromboxane (A2)-receptor antagonists.EBI
University of Pennsylvania
Design, synthesis, and biological evaluation of 1-phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as new glycogen synthase kinase-3ß inhibitors.EBI
University of Naples Federico II
Cyclopentane-1,3-dione: a novel isostere for the carboxylic acid functional group. Application to the design of potent thromboxane (A2) receptor antagonists.EBI
University of Pennsylvania
Investigation of 4-piperidinols as novel H3 antagonists.EBI
Athersys
3-Indolyl sultams as selective CRTh2 antagonists.EBI
Athersys
The design and synthesis of a tricyclic single-nitrogen scaffold that serves as a 5-HT2C receptor agonist.EBI
Athersys
The identification of pyrimidine-diazabicyclo[3.3.0]octane derivatives as 5-HT2C receptor agonists.EBI
Athersys
Isosteric ramatroban analogs: selective and potent CRTH-2 antagonists.EBI
Athersys
1,2,4-Triazolo[1,5-a]pyrimidines in drug design.EBI
University of California
Multitargeted Imidazoles: Potential Therapeutic Leads for Alzheimer's and Other Neurodegenerative Diseases.EBI
University of Pennsylvania
Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group.EBI
University of Pennsylvania