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10 articles for JD Burch


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Tetrahydroindazoles as Interleukin-2 Inducible T-Cell Kinase Inhibitors. Part II. Second-Generation Analogues with Enhanced Potency, Selectivity, and Pharmacodynamic Modulation in Vivo.EBI
Genentech
Design, synthesis and structure-activity relationships of a novel class of sulfonylpyridine inhibitors of Interleukin-2 inducible T-cell kinase (ITK).EBI
Evotec
Property- and structure-guided discovery of a tetrahydroindazole series of interleukin-2 inducible T-cell kinase inhibitors.EBI
Genentech
Discovery and optimization of indazoles as potent and selective interleukin-2 inducible T cell kinase (ITK) inhibitors.EBI
Genentech
Back pocket flexibility provides group II p21-activated kinase (PAK) selectivity for type I 1/2 kinase inhibitors.EBI
Genentech
Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK).EBI
Evotec (Uk)
Structure-activity relationships and pharmacokinetic parameters of quinoline acylsulfonamides as potent and selective antagonists of the EP(4) receptor.EBI
Merck Frosst Centre For Therapeutic Research
Naphthalene/quinoline amides and sulfonylureas as potent and selective antagonists of the EP4 receptor.EBI
Merck Frosst Centre For Therapeutic Research
Novel pyridone EPEBI
Inception Sciences Canada
Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-κB Inducing Kinase.EBI
Genentech