19 articles for PM Woster
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Discovery of a new class of histone deacetylase inhibitors with a novel zinc binding group.
Medical University of South Carolina
Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures.
John Hopkins University
Synthesis and evaluation of novel cyclic Peptide inhibitors of lysine-specific demethylase 1.
Medical University of South Carolina
Low molecular weight amidoximes that act as potent inhibitors of lysine-specific demethylase 1.
Wayne State University
(Bis)urea and (bis)thiourea inhibitors of lysine-specific demethylase 1 as epigenetic modulators.
Wayne State University
Terminally alkylated polyamine analogues as chemotherapeutic agents.
Wayne State University
S-(5'-deoxy-5'-adenosyl)-1-aminoxy-4-(methylsulfonio)-2-cyclopentene (AdoMao): an irreversible inhibitor of S-adenosylmethionine decarboxylase with potent in vitro antitrypanosomal activity.
Wayne State University
Restricted rotation analogs of S-adenosylmethionine: synthesis, evaluation as inhibitors of S-adenosylmethionine decarboxylase, and potential use as selective antitrypanosomal agents
TBA
-cyano-substituted analogoues of decarboxylated S-adenosylmethionine as enzyme activated, irreversible inhibitors of S-adenosylmethionine decarboxylase
TBA
Mechanism-based inhibitors of the aspartyl protease plasmepsin II as potential antimalarial agents.
Wayne State University
Synthesis and evaluation of small molecule inhibitors of LSD1 for use against MYCN-expressing neuroblastoma.
Medical University of South Carolina
Novel alkylpolyaminoguanidines and alkylpolyaminobiguanides with potent antitrypanosomal activity.
Wayne State University
3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors.
Medical University of South Carolina
Ligand modifications to reduce the relative resistance of multi-drug resistant HIV-1 protease.
Wayne State University
Recent advances in the development of polyamine analogues as antitumor agents.
Johns Hopkins University
Polyaminohydroxamic acids and polyaminobenzamides as isoform selective histone deacetylase inhibitors.
Wayne State University
Alkyl-substituted polyaminohydroxamic acids: a novel class of targeted histone deacetylase inhibitors.
Wayne State University