BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 772K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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16 articles for AD Michel

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
3
Antihypertensive 9-substituted 1-oxa-4,9-diazaspiro[5.5]undecan-3-ones.EBI
TBA
43
2-(Quinuclidin-3-yl)pyrido[4,3-b]indol-1-ones and isoquinolin-1-ones. Potent conformationally restricted 5-HT3 receptor antagonists.EBI
Syntex Research
51
Discovery of novel, non-acidic 1,5-biaryl pyrrole EP1 receptor antagonists.EBI
Glaxosmithkline
32
1,5-Biaryl pyrrole derivatives as EP1 receptor antagonists: Structure-activity relationships of 4- and 5-substituted benzoic acid derivatives.EBI
Glaxosmithkline
29
1,5-Biaryl pyrrole derivatives as EP1 receptor antagonists. Structure-activity relationships of 6-substituted and 5,6-disubstituted benzoic acid derivatives.EBI
Glaxosmithkline
20
Identification of 2-oxo-N-(phenylmethyl)-4-imidazolidinecarboxamide antagonists of the P2X(7) receptor.EBI
Glaxosmithkline
23
Discovery and structure-activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor.EBI
Glaxosmithkline
24
Structure-activity relationships and in vivo activity of (1H-pyrazol-4-yl)acetamide antagonists of the P2X(7) receptor.EBI
Glaxosmithkline
32
Synthesis and structure-activity relationships of a series of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor.EBI
Glaxosmithkline
1
Identification of novel glycine sulfonamide antagonists for the EP1 receptor.EBI
Glaxosmithkline
24
A novel series of benzimidazole NR2B-selective NMDA receptor antagonists.EBI
Glaxosmithkline
18
Synthesis and biological activity of a series of tetrasubstituted-imidazoles as P2X(7) antagonists.EBI
Glaxosmithkline
6
The discovery of 6-[2-(5-chloro-2-{[(2,4-difluorophenyl)methyl]oxy}phenyl)-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid, GW848687X, a potent and selective prostaglandin EP1 receptor antagonist for the treatment of inflammatory pain.EBI
Gsk
1
Structure-activity relationships of 1,5-biaryl pyrroles as EP1 receptor antagonists.EBI
Glaxosmithkline
9
Discovery of novel biaryl heterocyclic EP1 receptor antagonists.EBI
Glaxosmithkline
21
Discovery of {4-[4,9-bis(ethyloxy)-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl]-2-fluorophenyl}acetic acid (GSK726701A), a novel EPEBI
Glaxosmithkline