BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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8 articles for F Morandi

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Optimizing cell permeation of an antibiotic resistance inhibitor for improved efficacy.EBI
Università
Discovery of Orally Available and Brain Penetrant AEP Inhibitors.EBI
Roche Innovation Center Basel
Discovery of potent and selective reversible Bruton's tyrosine kinase inhibitors.EBI
Emd Serono Research & Development Institute
Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases.EBI
Merck
Discovery of BAY-298 and BAY-899: Tetrahydro-1,6-naphthyridine-Based, Potent, and Selective Antagonists of the Luteinizing Hormone Receptor Which Reduce Sex Hormone Levels in Vivo.EBI
Bayer
Discovery of a novel series of pyridine and pyrimidine carboxamides as potent and selective covalent inhibitors of Btk.EBI
Emd Serono Research & Development Institute
Optimization of the efflux ratio and permeability of covalent irreversible BTK inhibitors.EBI
Emd Serono Research & Development Institute
Discovery of potent, highly selective covalent irreversible BTK inhibitors from a fragment hit.EBI
Emd Serono Research & Development Institute