BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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15 articles for S Willems

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Structure-Guided Design of a Highly Potent Partial RXR Agonist with Superior Physicochemical Properties.EBI
Ludwig-Maximilians-Universitat (LMU) Munchen
Structural Optimization of Oxaprozin for Selective Inverse Nurr1 Agonism.EBI
Ludwig-Maximilians-University of Munich
Structural Fusion of Natural and Synthetic Ligand Features Boosts RXR Agonist Potency.EBI
Goethe University Frankfurt
Design of Nurr1 Agonists EBI
Ludwig Maximilian University of Munich
Targeting Nuclear Receptors in Neurodegeneration and Neuroinflammation.EBI
Goethe University Frankfurt
Medicinal Chemistry and Chemical Biology of Nurr1 Modulators: An Emerging Strategy in Neurodegeneration.EBI
Goethe University Frankfurt
Structure-Based Design of Dual Partial Peroxisome Proliferator-Activated Receptor γ Agonists/Soluble Epoxide Hydrolase Inhibitors.EBI
Goethe-University
A Photohormone for Light-Dependent Control of PPARα in Live Cells.EBI
Goethe-University Frankfurt
Propranolol Activates the Orphan Nuclear Receptor TLX to Counteract Proliferation and Migration of Glioblastoma Cells.EBI
Goethe-University Frankfurt
Development and Profiling of Inverse Agonist Tools for the Neuroprotective Transcription Factor Nurr1.EBI
Goethe University Frankfurt
Fragment-like Chloroquinolineamines Activate the Orphan Nuclear Receptor Nurr1 and Elucidate Activation Mechanisms.EBI
Goethe University
A New FXR Ligand Chemotype with Agonist/Antagonist Switch.EBI
Goethe-University Frankfurt
Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor γ (PPARγ).EBI
New York University
Design and Structural Optimization of Dual FXR/PPARδ Activators.EBI
Goethe University Frankfurt
Boosting Anti-Inflammatory Potency of Zafirlukast by Designed Polypharmacology.EBI
Goethe University Frankfurt