32 articles for C Hou
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Cmpds
Data
Article Title
Organization
16
Evaluation of anti-diabetic effect and gall bladder function with 2-thio-5-thiomethyl substituted imidazoles as TGR5 receptor agonists.
Janssen Research and Development
45
Discovery of Orally Efficacious Tetrahydrobenzimidazoles as TGR5 Agonists for Type 2 Diabetes.
Janssen Research and Development
23
Tetrahydropyrazolo[4,3-c]pyridine derivatives as potent and peripherally selective cannabinoid-1 (CB1) receptor inverse agonists.
Janssen Research and Development
23
Tetrahydroindazole derivatives as potent and peripherally selective cannabinoid-1 (CB1) receptor inverse agonists.
Janssen Research and Development
33
The discovery and SAR of cyclopenta[b]furans as inhibitors of CCR2.
Janssen Research and Development
30
Discovery and SAR of 5-aminooctahydrocyclopentapyrrole-3a-carboxamides as potent CCR2 antagonists.
Janssen Research and Development
25
A novel series of N-(azetidin-3-yl)-2-(heteroarylamino)acetamide CCR2 antagonists.
Janssen Research and Development
42
Novel 2-aminooctahydrocyclopentalene-3a-carboxamides as potent CCR2 antagonists.
Janssen Research and Development
28
Discovery of a 4-Azetidinyl-1-thiazoyl-cyclohexane CCR2 Antagonist as a Development Candidate.
TBA
33
Substituted dipiperidine alcohols as potent CCR2 antagonists.
Johnson & Johnson Pharmaceutical Research and Development
12
F-18 stilbenes as PET imaging agents for detecting beta-amyloid plaques in the brain.
University of Pennsylvania
45
The discovery of novel cyclohexylamide CCR2 antagonists.
Johnson & Johnson Pharmaceutical Research and Development
59
Design, synthesis and SAR of indazole and benzoisoxazole containing 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists.
Johnson & Johnson Pharmaceutical Research and Development
38
Overcoming hERG activity in the discovery of a series of 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists.
Johnson & Johnson Pharmaceutical Research and Development
9
Synthesis and structure-activity relationship of 7-azaindole piperidine derivatives as CCR2 antagonists.
Johnson & Johnson Pharmaceutical Research and Development
1
Discovery of the first potent ROR1 degrader for the treatment of non-small cell lung cancer.
Jinan University
30
Synthesis, structure-activity relationship and in vivo antiinflammatory efficacy of substituted dipiperidines as CCR2 antagonists.
Johnson & Johnson Pharmaceutical Research and Development
36
Synthesis and biological evaluation of phenyl piperidine derivatives as CCR2 antagonists.
Johnson & Johnson Pharmaceutical Research and Development
1
Discovery of LLC0424 as a Potent and Selective in Vivo NSD2 PROTAC Degrader.
Shanghai Institute of Organic Chemistry
31
Potent and selective CC-chemokine receptor-2 (CCR2) antagonists as a potential treatment for asthma.
Johnson & Johnson Pharmaceutical Research and Development
16
Discovery of Isoform-Selective Akt3 Degraders Overcoming Osimertinib-Induced Resistance in Non-Small Cell Lung Cancer Cells.
Jinan University
35
Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from
University of Kentucky
8
2-(2-(dimethylaminomethyl)phenoxy)-5-iodophenylamine: an improved serotonin transporter imaging agent.
University of Pennsylvania
11
Structure-activity relationship of imidazo[1,2-a]pyridines as ligands for detecting beta-amyloid plaques in the brain.
University of Pennsylvania
6
Isomerization of (Z,Z) to (E,E)1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene in strong base: probes for amyloid plaques in the brain.
University of Pennsylvania
7
Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates.
University of Pennsylvania
3
A new single-photon emission computed tomography imaging agent for serotonin transporters: [123I]IDAM, 5-iodo-2-((2-((dimethylamino)methyl)phenyl)thio)benzyl alcohol.
University of Pennsylvania
2
Synthesis and evaluation of indolinyl- and indolylphenylacetylenes as PET imaging agents for beta-amyloid plaques.
University of Pennsylvania
8
Radioiodinated aza-diphenylacetylenes as potential SPECT imaging agents for beta-amyloid plaque detection.
University of Pennsylvania
18
New diphenylacetylenes as probes for positron emission tomographic imaging of amyloid plaques.
University of Pennsylvania
12
Novel styrylpyridines as probes for SPECT imaging of amyloid plaques.
University of Pennsylvania