Binding Database

BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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10 articles for N Patel

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

Discovery and Development of LX7101, a Dual LIM-Kinase and ROCK Inhibitor for the Treatment of Glaucoma.

Lexicon Pharmaceuticals

A fluorescent reporter of ATP binding-competent receptor kinases.

University of Miami

Discovery of PF-04449913, a Potent and Orally Bioavailable Inhibitor of Smoothened.

TBA

Structure-activity relationships of some opiate glycosides.

Ultrafine Ufc

Novel 3-Aryl Indoles as Progesterone Receptor Antagonists for Uterine Fibroids

TBA

Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma.

Lexicon Pharmaceuticals

PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.

University of California-San Diego

Defining Target Engagement Required for Efficacy

Lilly Research Laboratories

Synthesis and evaluation of a 125I-labeled iminodihydroquinoline-derived tracer for imaging of voltage-gated sodium channels.

Institute of Nuclear Medicine

Discovery of 5-substituted 2-amino-4-chloro-8-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-7,8-dihydropteridin-6(5H)-ones as potent and selective Hsp90 inhibitors.

Poniard Pharmaceuticals