The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

9 articles for K Ohgane


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Structure-activity relationships of oxysterol-derived pharmacological chaperones for Niemann-Pick type C1 protein.EBI
The University of Tokyo
Structure-activity relationship studies of Niemann-Pick type C1-like 1 (NPC1L1) ligands identified by screening assay monitoring pharmacological chaperone effect.EBI
The University of Tokyo
Design, synthesis, and biological evaluation of novel transrepression-selective liver X receptor (LXR) ligands with 5,11-dihydro-5-methyl-11-methylene-6H-dibenz[b,e]azepin-6-one skeleton.EBI
The University of Tokyo
Plakevulin A induces apoptosis and suppresses IL-6-induced STAT3 activation in HL60 cells.EBI
Tokyo University of Science
Fine-tuning of nitrogen-containing bisphosphonate esters that potently induce degradation of HMG-CoA reductase.EBI
Tokyo University of Science
Bisphosphonate esters interact with HMG-CoA reductase membrane domain to induce its degradation.EBI
The University of Tokyo
Luciferase-based HMG-CoA reductase degradation assay for activity and selectivity profiling of oxy(lano)sterols.EBI
The University of Tokyo
Structure-activity relationship study of estrogen receptor down-regulators with a diphenylmethane skeleton.EBI
The University of Tokyo
Phenanthridin-6-one derivatives as the first class of non-steroidal pharmacological chaperones for Niemann-Pick disease type C1 protein.EBI
The University of Tokyo