BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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10 articles for P Lockey

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Identification of N-sulfonyl-tetrahydroquinolines as RORc inverse agonists.EBI
Genentech
Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of Action.EBI
Genentech
Reduction in lipophilicity improved the solubility, plasma-protein binding, and permeability of tertiary sulfonamide RORc inverse agonists.EBI
Genentech
A reversed sulfonamide series of selective RORc inverse agonists.EBI
Argenta Discovery
Identification of tertiary sulfonamides as RORc inverse agonists.EBI
Genentech
Structure-based design of substituted hexafluoroisopropanol-arylsulfonamides as modulators of RORc.EBI
Genentech
Discovery of a novel non-steroidal GR antagonist with in vivo efficacy in the olanzapine-induced weight gain model in the rat.EBI
Corcept Therapeutics
1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity.EBI
Corcept Therapeutics
Structure-activity relationships of a novel series of melanin-concentrating hormone (MCH) receptor antagonists.EBI
Argenta Discovery
Selective endothelin A receptor antagonists. 4. Discovery and structure-activity relationships of stilbene acid and alcohol derivatives.EBI
RhôNe-Poulenc Rorer