BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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11 articles for TR Ryder

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis of quaternarya-amino acid-based arginase inhibitors via the Ugi reaction.EBI
Institutes For Pharmaceutical Discovery
2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors.EBI
Institutes For Pharmaceutical Discovery
Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potent inhibitors of human arginases I and II for treatment of myocardial reperfusion injury.EBI
Institutes For Pharmaceutical Discovery
The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.EBI
Pfizer
Synthesis of a series of 4-benzyloxyaniline analogues as neuronal N-type calcium channel blockers with improved anticonvulsant and analgesic properties.EBI
Warner-Lambert
Structure-activity relationship at the proximal phenyl group in a series of non-peptidyl N-type calcium channel antagonists.EBI
Parke-Davis Pharmaceutical Research
Structure-activity relationship of N-methyl-N-aralkyl-peptidylamines as novel N-type calcium channel blockers.EBI
Warner-Lambert
Multiple parallel synthesis of N,N-dialkyldipeptidylamines as N-type calcium channel blockers.EBI
Warner-Lambert
Synthesis and biological evaluation of substituted 4-(OBz)phenylalanine derivatives as novel N-type calcium channel blockers.EBI
Warner-Lambert
N,N-dialkyl-dipeptidylamines as novel N-type calcium channel blockers.EBI
Warner-Lambert
Rapid optimization of an ICE inhibitor synthesis using multiple reaction conditions in a parallel array.EBI
Warner-Lambert