BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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7 articles for S Maddileti

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Molecular modeling of the human P2Y2 receptor and design of a selective agonist, 2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate.EBI
National Institute of Diabetes and Digestive and Kidney Diseases
Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor.EBI
National Institute of Diabetes and Digestive and Kidney Diseases
Adenine nucleotide analogues locked in a Northern methanocarba conformation: enhanced stability and potency as P2Y(1) receptor agonists.EBI
National Institute of Diabetes
Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors.EBI
National Institute of Diabetes
P2Y1 antagonists: combining receptor-based modeling and QSAR for a quantitative prediction of the biological activity based on consensus scoring.EBI
National Institute of Diabetes and Digestive and Kidney Diseases
Human P2Y(6) receptor: molecular modeling leads to the rational design of a novel agonist based on a unique conformational preference.EBI
Niddk
2-Substitution of adenine nucleotide analogues containing a bicyclo[3.1.0]hexane ring system locked in a northern conformation: enhanced potency as P2Y1 receptor antagonists.EBI
Niddk