BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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7 articles for RW Spencer

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Design and synthesis of 4H-3,1-benzoxazin-4-ones as potent alternate substrate inhibitors of human leukocyte elastase.EBI
Syntex Research
Inhibition of human leukocyte elastase, porcine pancreatic elastase, and chymotrypsin by elasnin and other 4-hydroxy-2-pyrones.EBI
TBA
Design of alternate substrate inhibitors of serine proteases. Synergistic use of alkyl substitution to impede enzyme-catalyzed deacylation.EBI
TBA
 
Inhibition of human leukocyte elastase (HLE) by novel bicyclic β-lactamsEBI
TBA
 
CP-70,030 and CP-75,998: The first non-peptide antagonists of bombesin and gastrin releasing peptideEBI
TBA
 
Physical parameters for brian uptake: optimizing log P, log D and pKa of T H AEBI
TBA
 
Novel in vitro and in vivo inhibitors of prolyl endopeptidaseEBI
TBA