Binding Database

BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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14 articles for J King-Underwood

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

Discovery of Narrow Spectrum Kinase Inhibitors: New Therapeutic Agents for the Treatment of COPD and Steroid-Resistant Asthma.

Sygnature Discovery

The identification of alpha-ketoamides as potent inhibitors of hepatitis C virus NS3-4A proteinase.

Roche Discover Welwyn

Discovery of novel benzothienoazepine derivatives as potent inhibitors of respiratory syncytial virus.

Sygnature Discovery

Combination Therapy Comprising A2A/A2B and PD-1/PD-L1 Inhibitors

Incyte

Immunomodulator compounds and methods of use

Incyte

Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity

Boehringer Ingelheim International

Urease inhibitors from Indigofera gerardiana Wall.

Khyber Medical College

Oligomer-opioid agonist conjugates

Nektar Therapeutics

Proline sulfonamide derivatives as orexin receptor antagonists

Actelion Pharmaceuticals

Benzodioxole piperidine compounds

Hoffmann-La Roche

Structure-based design and solid-phase parallel synthesis of phosphorylated nonpeptides to explore hydrophobic binding at the Src SH2 domain.

Ariad Pharmaceuticals

Steady-state kinetic mechanism of Ras farnesyl:protein transferase.

Merck Research Laboratories

Reaction of the molybdenum- and copper-containing carbon monoxide dehydrogenase from Oligotropha carboxydovorans with quinones.

University of California Riverside

N-(3-lodoprop-2E-enyl)-2beta-carbomethoxy-3beta-(3',4'-dichloro phenyl)nortropane (beta-CDIT), a tropane derivative: pharmacological characterization as a specific ligand for the dopamine transporter in the rodent brain.

University of Tours