19 articles for EM Seward
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Cmpds
Data
Article Title
Organization
15
Discovery of selective and noncovalent diaminopyrimidine-based inhibitors of epidermal growth factor receptor containing the T790M resistance mutation.
Genentech
36
Novel 5-HT3 antagonists: indol-3-ylspiro(azabicycloalkane-3,5'(4'H)-oxazoles).
Merck Sharp and Dohme Research Laboratories
49
Novel 5-HT3 antagonists. Indole oxadiazoles.
Merck Sharp and Dohme Research Laboratories
16
Identification of GNE-293, a potent and selective PI3Kd inhibitor: navigating in vitro genotoxicity while improving potency and selectivity.
Genentech
30
Discovery of novel PI3-kinased specific inhibitors for the treatment of rheumatoid arthritis: taming CYP3A4 time-dependent inhibition.
Genentech
9
Potent and selective inhibitors of PI3Kd: obtaining isoform selectivity from the affinity pocket and tryptophan shelf.
Genentech
4
Quinuclidine based NK-1 antagonists 2: determination of the absolute stereochemical requirements
TBA
22
Discovery of a Noncovalent, Mutant-Selective Epidermal Growth Factor Receptor Inhibitor.
Charles River Laboratories
19
Spirocyclic NK(1) antagonists I: [4.5] and [5.5]-spiroketals.
Merck Sharp and Dohme Research Laboratories
11
N-heteroaryl-2-phenyl-3-(benzyloxy)piperidines: a novel class of potent orally active human NK1 antagonists.
Merck Sharp and Dohme Research Laboratories
55
Identification of a series of 3-(benzyloxy)-1-azabicyclo[2.2.2]octane human NK1 antagonists.
Merck Sharp and Dohme Research Laboratories
12
Design of Selective Benzoxazepin PI3Kδ Inhibitors Through Control of Dihedral Angles.
Genentech
95
3-BETA-HSD1 INHIBITORS AND COMPOSITIONS AND USES THEREOF
The Cleveland Clinic Foundation
22
PYRROLO[1,2-b]-2-PYRIDAZINONE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS
Suven Life Sciences