15 articles for P Dokurno
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution.
Vernalis (R&D)
Fatty acid amide hydrolase inhibitors. Surprising selectivity of chiral azetidine ureas.
Vernalis (R&D)
A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase.
Daiichi Sankyo Co.
Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors.
Servier Research Institute of Medicinal Chemistry
Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1B.
Vernalis (R&D)
Discovery of S64315, a Potent and Selective Mcl-1 Inhibitor.
Servier Research Institute of Medicinal Chemistry
Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity.
Servier Research Institute of Medicinal Chemistry
Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1).
Vernalis (R&D)
Substituted pyridine derivatives useful as c-fms kinase inhibitors
Janssen Pharmaceutica