BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 760K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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13 articles for HR Chobanian

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
The design and synthesis of novel spirocyclic heterocyclic sulfone ROMK inhibitors as diuretics.EBI
Merck
Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain.EBI
Merck Research Laboratories
Discovery of benzodiazepine sulfonamide-based bombesin receptor subtype 3 agonists and their unusual chirality.EBI
TBA
Discovery of MK-7725, A Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity.EBI
TBA
The design and synthesis of potent, selective benzodiazepine sulfonamide bombesin receptor subtype 3 (BRS-3) agonists with an increased barrier of atropisomerization.EBI
Merck Research Laboratories
Pyridinesulfonylureas and pyridinesulfonamides as selective bombesin receptor subtype-3 (BRS-3) agonists.EBI
Merck Research Laboratories
Discovery of MK-8153, a Potent and Selective ROMK Inhibitor and Novel Diuretic/Natriuretic.EBI
Merck
Design, synthesis and biological evaluation of indane derived GPR40 agoPAMs.EBI
Merck
Structure-Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs.EBI
Merck
INDAZOLES AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) INHIBITORS AND METHODS FOR USING SAMEBDB
1ST Biotherapeutics
3-arylindazoles as selective MEK4 inhibitorsBDB
Northwestern University
Amido-benzyl sulfone and sulfoxide derivatesBDB
TBA
In vitro receptor screening of pure constituents of St. John's wort reveals novel interactions with a number of GPCRs.BDB
WestfÄLische Wilhelms-UniversitÄ