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18 articles for WT Ashton


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Inhibition of the mammalian beta-lactamase renal dipeptidase (dehydropeptidase-I) by (Z)-2-(acylamino)-3-substituted-propenoic acids.EBI
TBA
 
Potent triazolinone-based angiotensin II receptor antagonists with equivalent affinity for both the AT1 and AT2 subtypesEBI
TBA
 
Triazolinones as nonpeptide angiotensin II antagonists. 2. discovery of a potent and orally active triazolinone acylsulfonamideEBI
TBA
 
Synthesis and structure-activity relationships of a novel series of non-peptide AT2-selective angiotensin II receptor antagonistsEBI
TBA
Diastereoselective synthesis and configuration-dependent activity of (3-substituted-cycloalkyl)glycine pyrrolidides and thiazolidides as dipeptidyl peptidase IV inhibitors.EBI
Merck Research Laboratories
Orally bioavailable, indole-based nonpeptide GnRH receptor antagonists with high potency and functional activity.EBI
Merck Research Laboratories
Potent nonpeptide GnRH receptor antagonists derived from substituted indole-5-carboxamides and -acetamides bearing a pyridine side-chain terminus.EBI
Merck Research Laboratories
Substituted indole-5-carboxamides and -acetamides as potent nonpeptide GnRH receptor antagonists.EBI
Merck Research Laboratories
Structure-activity relationships of biphenyl tetrazoles as metallo-beta-lactamase inhibitors.EBI
Merck Research Laboratories
Nonpeptide angiotensin II antagonists derived from 4H-1,2,4-triazoles and 3H-imidazo[1,2-b][1,2,4]triazoles.EBI
Merck Research Laboratories
Triazolinones as nonpeptide angiotensin II antagonists. 1. Synthesis and evaluation of potent 2,4,5-trisubstituted triazolinones.EBI
Merck Research Laboratories
Nonpeptide angiotensin II antagonists derived from 1H-pyrazole-5-carboxylates and 4-aryl-1H-imidazole-5-carboxylates.EBI
Merck Research Laboratories
Triazolinone biphenylsulfonamide derivatives as orally active angiotensin II antagonists with potent AT1 receptor affinity and enhanced AT2 affinity.EBI
Merck Research Laboratories
Triazolinone biphenylsulfonamides as angiotensin II receptor antagonists with high affinity for both the AT1 and AT2 subtypes.EBI
Merck Research Laboratories
Potent and orally active angiotensin II receptor antagonists with equal affinity for human AT1 and AT2 subtypes.EBI
Merck Research Laboratories
Renin inhibitors containing C-termini derived from mercaptoheterocycles.EBI
Merck Sharp & Dohme Research Laboratories
Inhibitors of human renin with C-termini derived from amides and esters of alpha-mercaptoalkanoic acids.EBI
Merck Research Laboratories
1,3,4-thiadiazole compounds and their use in treating cancerBDB
Astrazeneca