BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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11 articles for G Kontopidis

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Iterative conversion of cyclin binding groove peptides into druglike CDK inhibitors with antitumor activity.EBI
University of South Carolina
Design, synthesis, and evaluation of 2-methyl- and 2-amino-N-aryl-4,5-dihydrothiazolo[4,5-h]quinazolin-8-amines as ring-constrained 2-anilino-4-(thiazol-5-yl)pyrimidine cyclin-dependent kinase inhibitors.EBI
University of St. Andrews
Discovery of N-phenyl-4-(thiazol-5-yl)pyrimidin-2-amine aurora kinase inhibitors.EBI
Cyclacel
Strong Binding of EBI
University of Debrecen
Discovery of Small-Molecule Inhibitors of Receptor Activator of Nuclear Factor-κB Ligand with a Superior Therapeutic Index.EBI
Agricultural University of Athens
Design and Synthesis of Type-IV Inhibitors of BRAF Kinase That Block Dimerization and Overcome Paradoxical MEK/ERK Activation.EBI
University of South Carolina
Optimization of non-ATP competitive CDK/cyclin groove inhibitors through REPLACE-mediated fragment assembly.EBI
University of South Carolina
Inhibitors of IRAK4 activityBDB
Merck Sharp & Dohme
Hydrophobically tagged janus kinase inhibitors and uses thereofBDB
Dana-Farber Cancer Institute
Pyrrolopyridazine inhibitors of IRAK4 activityBDB
Merck Sharp & Dohme
Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 4: functionalization of the benzopyran A-ring.BDB
Eli Lilly