The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

19 articles for M Winn


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Conformationally defined adrenergic agents. 2. Catechol imidazoline derivatives: biological effects at alpha 1 and alpha 2 adrenergic receptors.EBI
TBA
Conformationally defined adrenergic agents. 1. Design and synthesis of novel alpha 2 selective adrenergic agents: electrostatic repulsion based conformational prototypes.EBI
TBA
 
Synthesis and In Vitro evaluation of fused ring heterocyle-containing angiotensin II antagonists.EBI
TBA
2-(Alkylamino)nicotinic acid and analogs. Potent angiotensin II antagonists.EBI
Abbott Laboratories
Synthesis and biological evaluation of novel, selective, nonsteroidal glucocorticoid receptor antagonists.EBI
Abbott Laboratories
Pharmacology of endothelin receptor antagonists ABT-627, ABT-546, A-182086 and A-192621: in vitro studies.EBI
Abbott Laboratories
Adamantane sulfone and sulfonamide 11-beta-HSD1 Inhibitors.EBI
Abbott Laboratories
Discovery of potent and selective inhibitors of 11beta-HSD1 for the treatment of metabolic syndrome.EBI
Abbott Laboratories
Discovery of novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. 4. Structure-activity relationship of substituents on the benzene ring of the cinnamide.EBI
Abbott Laboratories
Pyrrolidine-3-carboxylic acids as endothelin antagonists. 5. Highly selective, potent, and orally active ET(A) antagonists.EBI
Abbott Laboratories
Design, synthesis, and activity of a series of pyrrolidine-3-carboxylic acid-based, highly specific, orally active ET(B) antagonists containing a diphenylmethylamine acetamide side chain.EBI
Abbott Laboratories
Pyrrolidine-3-carboxylic acids as endothelin antagonists. 4. Side chain conformational restriction leads to ET(B) selectivity.EBI
Abbott Laboratories
Pyrrolidine-3-carboxylic acids as endothelin antagonists. 3. Discovery of a potent, 2-nonaryl, highly selective ETA antagonist (A-216546).EBI
Abbott Laboratories
Pyrrolidine-3-carboxylic acids as endothelin antagonists. 2. Sulfonamide-based ETA/ETB mixed antagonists.EBI
Abbott Laboratories
Potent and selective non-benzodioxole-containing endothelin-A receptor antagonists.EBI
Abbott Laboratories
2,4-Diarylpyrrolidine-3-carboxylic acids--potent ETA selective endothelin receptor antagonists. 1. Discovery of A-127722.EBI
Abbott Laboratories
Discovery of a novel class of orally active, non-peptide angiotensin II antagonists.EBI
Abbott Laboratories
Heteroaromatic compounds and their use as dopamine D1 ligandsBDB
Pfizer
Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase.BDB
Sugen