BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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17 articles for S Fung

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain.EBI
Merck Research Laboratories
Discovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide Hydrolase.EBI
Merck Research Laboratories
Parallel strategies for the preparation and selection of liver-targeted glucocorticoid receptor antagonists.EBI
Abbott Laboratories
Synthesis and activity of novel bile-acid conjugated glucocorticoid receptor antagonists.EBI
Abbott Laboratories
Liver-selective glucocorticoid antagonists: a novel treatment for type 2 diabetes.EBI
Abbott Laboratories
Synthesis, activity, metabolic stability, and pharmacokinetics of glucocorticoid receptor modulator-statin hybrids.EBI
Abbott Laboratories
Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.EBI
Abbott Laboratories
Adamantane sulfone and sulfonamide 11-beta-HSD1 Inhibitors.EBI
Abbott Laboratories
Discovery of potent and selective inhibitors of 11beta-HSD1 for the treatment of metabolic syndrome.EBI
Abbott Laboratories
Adamantane 11-beta-HSD-1 inhibitors: Application of an isocyanide multicomponent reaction.EBI
Abbott Laboratories
Discovery of orally active butyrolactam 11beta-HSD1 inhibitors.EBI
Abbott Laboratories
Synthesis and biological evaluation of heterocycle containing adamantane 11beta-HSD1 inhibitors.EBI
Abbott Laboratories
Synthesis and structural activity relationship of 11beta-HSD1 inhibitors with novel adamantane replacements.EBI
Abbott Laboratories
N-[5-(trifluoromethyl)-6-methoxy-1-naphthalenyl]thioxomethyl]- N-methylglycine (Tolrestat), a potent, orally active aldose reductase inhibitor.EBI
TBA
Heterocyclylalkyne derivatives and their use as modulators of mGluR5 receptorsBDB
Recordati Ireland
Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase.BDB
Sugen