BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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17 articles for R Kurukulasuriya

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of Novel Indoline Cholesterol Ester Transfer Protein Inhibitors (CETP) through a Structure-Guided Approach.EBI
Merck Research Laboratories
Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1EBI
Merck
Discovery of orally active butyrolactam 11beta-HSD1 inhibitors.EBI
Abbott Laboratories
Synthesis and biological evaluation of heterocycle containing adamantane 11beta-HSD1 inhibitors.EBI
Abbott Laboratories
Synthesis and structural activity relationship of 11beta-HSD1 inhibitors with novel adamantane replacements.EBI
Abbott Laboratories
Optimization of brain-penetrant picolinamide derived leucine-rich repeat kinase 2 (LRRK2) inhibitors.EBI
Merck
Biaryl amide glucagon receptor antagonists.EBI
Abbott Laboratories
Discovery and development of benzo-[1,2,4]-triazolo-[1,4]-oxazepine GPR142 agonists for the treatment of diabetes.EBI
Merck Research Laboratories
Discovery of Amino-cyclobutarene-derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors for Cancer Immunotherapy.EBI
Merck
Development of indazole mineralocorticoid receptor antagonists and investigation into their selective late-stage functionalization.EBI
Merck
ARYLCYCLOHEXYLAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC DISORDERSBDB
Gilgamesh Pharmaceuticals
Purine inhibitors of human phosphatidylinositol 3-kinase deltaBDB
Merck Sharp & Dohme
Heteroaromatic compounds and their use as dopamine D1 ligandsBDB
Pfizer
N-[4-(quinolin-4-yloxy)cyclohexyl(methyl)](hetero)arylcarboxamides as androgen receptor antagonists, production and use thereof as medicinal productsBDB
Bayer Pharma Aktiengesellschaft
1-[m-carboxamido(hetero)aryl-methyl]-heterocyclyl-carboxamide derivativesBDB
Actelion Pharmaceuticals
A newly synthesized selective casein kinase I inhibitor, N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide, and affinity purification of casein kinase I from bovine testis.BDB
Nagoya University School of Medicine
Structural and biochemical characterization of Mycobacterium tuberculosis CYP142: evidence for multiple cholesterol 27-hydroxylase activities in a human pathogen.BDB
Manchester Interdisciplinary Biocentre