The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

28 articles for Z Liang


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis and evaluation of 2,5 and 2,6 pyridine-based CXCR4 inhibitors.EBI
Georgia State University
Design and synthesis of novel 3-sulfonylpyrazol-4-amino pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.EBI
Beijing Pearl Biotech
Discovery of 2-arylamino-4-(1-methyl-3-isopropylsulfonyl-4-pyrazol-amino)pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.EBI
Beijing Pearl Biotech
The discovery of potent agonists for GPR88, an orphan GPCR, for the potential treatment of CNS disorders.EBI
Lexicon Pharmaceuticals
Design, synthesis, and evaluation of phenylglycinols and phenyl amines as agonists of GPR88.EBI
Bristol-Myers Squibb
Synthesis and biological evaluation of 2-amino-5-aryl-3-benzylthiopyridine scaffold based potent c-Met inhibitors.EBI
Chinese Academy of Sciences
Novel 5-(benzyloxy)pyridin-2(1H)-one derivatives as potent c-Met inhibitors.EBI
Chinese Academy of Sciences
Anthraquinone Derivatives as Potent Inhibitors of c-Met Kinase and the Extracellular Signaling Pathway.EBI
Soochow University
Pharmacophore-based virtual screening and biological evaluation of small molecule inhibitors for protein arginine methylation.EBI
Georgia State University
Discovery of piragliatin--first glucokinase activator studied in type 2 diabetic patients.EBI
Hoffmann-La Roche
Discovery of novel 2-aminopyridine-3-carboxamides as c-Met kinase inhibitors.EBI
Chinese Academy of Sciences
Dipyrimidine amines: a novel class of chemokine receptor type 4 antagonists with high specificity.EBI
Emory University
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.EBI
Chinese Academy of Sciences
Identification and synthesis of N'-(2-oxoindolin-3-ylidene)hydrazide derivatives against c-Met kinase.EBI
Chinese Academy of Sciences
Design, synthesis, and biological evaluation of novel highly selective non-carboxylic acid FABP1 inhibitors.EBI
Guangdong Pharmaceutical University
Targeting the pyruvate dehydrogenase complex/pyruvate dehydrogenase kinase (PDC/PDK) axis to discover potent PDK inhibitors through structure-based virtual screening and pharmacological evaluation.EBI
Chongqing Medical and Pharmaceutical College
Discovery of small molecule CXCR4 antagonists.EBI
Emory University
Synthesis and bioactive evaluation of EBI
Guangxi University
Discovery of Orally Bioavailable EBI
China Pharmaceutical University
LXR-Mediated Regulation of Marine-Derived Piericidins Aggravates High-Cholesterol Diet-Induced Cholesterol Metabolism Disorder in Mice.EBI
Southern Medical University
Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family.EBI
Soochow University
Ene-yne Hydroquinones from a Marine-derived Strain of the Fungus EBI
Chinese Academy of Sciences
Exploring the Natural Piericidins as Anti-Renal Cell Carcinoma Agents Targeting Peroxiredoxin 1.EBI
Chinese Academy of Sciences
Preliminary evaluation of fluoro-pegylated benzyloxybenzenes for quantification of β-amyloid plaques by positron emission tomography.EBI
Beijing Normal University
Toll-like receptor 7 (TLR7) agonists having a pyridine or pyrazine moiety, conjugates thereof, and methods and uses thereforBDB
Bristol-Myers Squibb
Prodrug amino acid derivativeBDB
Taisho Pharmaceutical
Synthesis and HIV-1 RT inhibitory action of novel (4/6-substituted benzo[d]thiazol -2-yl)thiazolidin-4-ones. Divergence from the non-competitive inhibition mechanism.BDB
Aristotle University of Thessaloniki
Mechanistic studies of inactivation of inducible nitric oxide synthase by amidines.BDB
Northwestern University