BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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8 articles for JR Somoza

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
2,4,6-Triaminopyrimidine as a Novel Hinge Binder in a Series of PI3Kd Selective Inhibitors.EBI
Gilead Sciences
Design of novel, potent, and selective human beta-tryptase inhibitors based on alpha-keto-[1,2,4]-oxadiazoles.EBI
Celera
Design and synthesis of tri-ring P3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin K.EBI
Celera Genomics
Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic Stability.EBI
Gilead Sciences
Atropisomerism by Design: Discovery of a Selective and Stable Phosphoinositide 3-Kinase (PI3K) β Inhibitor.EBI
Gilead Sciences
Tricyclic DLK inhibitors and uses thereofBDB
Genentech
Pyrazolo[3,4-d]pyrimidine compounds, their preparation and use as sigma ligandsBDB
Laboratorios Del Dr. Esteve
Systematic structure-based design and stereoselective synthesis of novel multisubstituted cyclopentane derivatives with potent antiinfluenza activity.BDB
Biocryst Pharmaceuticals